STXBP2 抗体 (pSer513)
Quick Overview for STXBP2 抗体 (pSer513) (ABIN361480)
抗原
See all STXBP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer513
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特异性
- Specific for the ~65k Munc-18 protein phosphorylated at Ser515. Immunolabeling is blocked by the phosphopeptide used as antigen but not by the corresponding dephosphopeptide.
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交叉反应
- 大鼠
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预测反应
- bovine, canine, chicken, human, mouse, non-human primate, Xenopus
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纯化方法
- Antigen Affinity Purified from Pooled Serum
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免疫原
- Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser513 conjugated to KLH
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anti-Syntaxin Binding Protein 2 (STXBP2) antibody
STXBP2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 2 (STXBP2) (AA 1-280) antibodySTXBP2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 2 (STXBP2) antibodySTXBP2 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 2 (STXBP2) (AA 58-70) antibodySTXBP2 适用: 人, 小鼠, 大鼠, Cow, 犬, Hamster, 马, 猴, Pig, 非洲爪蟾 WB, IHC, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 2 (STXBP2) antibodySTXBP2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 2 (STXBP2) (AA 1-280) antibodySTXBP2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Syntaxin Binding Protein 2 (STXBP2) antibodySTXBP2 适用: 小鼠, 大鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended Dilution: WB: 1:1000 IHC: 1:400 Quality Control: Western blots performed on each lot.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
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储存条件
- -20 °C
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- STXBP2 (Syntaxin Binding Protein 2 (STXBP2))
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别名
- STXBP2
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背景
- Munc-18 ( mammalian homologue of Unc-18) is a protein that is thought to be involved in regulating exocytosis due, at least in part, to it ability to bind syntaxin (Ciufo et al., 2005). Munc18-1 is a neuron-specific member of the Sec1/Munc18 protein family that binds to syntaxin1A and is thought to stabilize the complex (Liu et al., 2004). The function of Munc-18 is thought to be regulated by PKC phosphorylation of Ser515 on the Munc-18 protein (Sassa et al., 1996). Anti-Phospho-Ser515 Munc-18 Western blot of rat cortex lysate showing specific immunolabeling of the ~65k Munc-18 protein phosphorylated at Ser515. Immunolabeling is blocked by the phosphopeptide (peptide) used as antigen but not by the corresponding dephosphopeptide (not shown). .
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分子量
- '65 kDa
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基因ID
- 81804
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UniProt
- Q62753
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
抗原
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