SLC6A1 抗体 (C-Term)
Quick Overview for SLC6A1 抗体 (C-Term) (ABIN361450)
抗原
See all SLC6A1 (GAT1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Specific for the ~67k GAT-1 protein. Immunolabeling is blocked by the peptide used as antigen.
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Affinity Purified
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免疫原
- Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH
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anti-GABA Transporter 1 (GAT1) (AA 585-599) antibody
GAT1 适用: 大鼠, 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-GABA Transporter 1 (GAT1) antibodyGAT1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GABA Transporter 1 (GAT1) antibodyGAT1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GABA Transporter 1 (GAT1) (Internal Region) antibodyGAT1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-GABA Transporter 1 (GAT1) antibodyGAT1 适用: 大鼠, 小鼠 WB, IHC, ICC, IP 宿主: 豚鼠 Polyclonal unconjugated
anti-GABA Transporter 1 (GAT1) (AA 473-487), (C-Term) antibodyGAT1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GABA Transporter 1 (GAT1) (Middle Region) antibodyGAT1 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-GABA Transporter 1 (GAT1) (C-Term) antibodyGAT1 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GABA Transporter 1 (GAT1) antibodyGAT1 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-GABA Transporter 1 (GAT1) (AA 251-300) antibodyGAT1 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 猴, Pig, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended Dilution: WB: 1:1000 IHC: 1:100-1:200 Quality Control: Western blots performed on each lot.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
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储存条件
- -20 °C
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- SLC6A1 (GAT1) (GABA Transporter 1 (GAT1))
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别名
- SLC6A1
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背景
- Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-1, the most abundant of the transporters, is found predominantly in neurons, but also in some specialized glia (Minelli et al., 1995). GAT-1 is thought to play a key role in epileptogenesis (Zhao et al. 2003). Anti-GAT1 Western blot of rat hippocampal homogenate showing specific immunolabeling of the~ 67k GAT-1 protein.
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分子量
- '67 kDa
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基因ID
- 79212
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UniProt
- P23978
抗原
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