NMDAR2A 抗体 (C-Term)
(1 reference)-
- 抗原 See all NMDAR2A (GRIN2A) 抗体
- NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))
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抗原表位
- C-Term
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NMDAR2A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- 特异性
- Specific for the ~180k NR2A subunit of the NMDA receptor. Recognizes human, mouse and rat forms of the NR2A subunit of NMDAR. No reactivity towards the NR2B and NR2C subunits. Immunolabeling is blocked by pre-adsorption of antibody with the fusion protein used to generate the antibody.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Antigen Affinity Purified from Pooled Serum
- 免疫原
- Fusion protein from the C-terminal region of the NR2A subunit
- Top Product
- Discover our top product GRIN2A Primary Antibody
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anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 851-950) antibody
GRIN2A 适用: 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 501-750) antibodyGRIN2A 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 1130-1400) antibodyGRIN2A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 23-165) antibodyGRIN2A 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3G10F9 unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibodyGRIN2A 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S327-95 unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibodyGRIN2A 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S327A-38 unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibody (HRP)GRIN2A 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S327-95 HRP
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibody (HRP)GRIN2A 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S327A-38 HRP
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibody (FITC)GRIN2A 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S327-95 FITC
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibody (FITC)GRIN2A 适用: 大鼠 WB, IHC, IF, ICC 宿主: 小鼠 Monoclonal S327A-38 FITC
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- 应用备注
- Recommended Dilution: WB: 1:1000 IHC (frozen sections, unpublished observations): 1:1000 to 1:2000 IP: 3 µl per 200 µg lysate Quality Control: Western blots performed on each lot.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized
- 储存条件
- -20 °C
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: "Autism-like behaviours and enhanced memory formation and synaptic plasticity in Lrfn2/SALM1-deficient mice." in: Nature communications, Vol. 8, pp. 15800, (2018) (PubMed).
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: "Autism-like behaviours and enhanced memory formation and synaptic plasticity in Lrfn2/SALM1-deficient mice." in: Nature communications, Vol. 8, pp. 15800, (2018) (PubMed).
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- 抗原
- NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))
- 别名
- GRIN2A (GRIN2A 产品)
- 别名
- NMDAR2A antibody, nr2a antibody, GRIN2A antibody, EPND antibody, GluN2A antibody, NR2A antibody, glutamate ionotropic receptor NMDA type subunit 2A antibody, glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog antibody, glutamate receptor ionotropic, NMDA 2A antibody, glutamate receptor, ionotropic, NMDA2A (epsilon 1) antibody, GRIN2A antibody, grin2a.L antibody, LOC100438553 antibody, Grin2a antibody
- 背景
- The ion channels activated by glutamate are typically divided into two classes. Glutamate receptors that are activated by kainate and a-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death (Grosshans et al., 2002, Wenthold et al., 2003, Carroll and Zukin, 2002). The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS (Lovinger et al., 1989, Alvestad et al., 2003, Snell et al., 1996). The NMDAR is also potentiated by protein phosphorylation (Lu et al., 1999). The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits. Anti-NMDA Receptor, NR2A Subunit Western blot of 10 ug of rat hippocampal (Hipp) lysate showing specific immunolabeling of the ~180k NR2A subunit of the NMDA receptor.
- 分子量
- '180 kDa
- 基因ID
- 24409
- UniProt
- Q00959
- 途径
- Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity
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