Retinoic Acid Receptor beta 抗体 (N-Term)
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- 抗原 See all Retinoic Acid Receptor beta (RARB) 抗体
- Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Retinoic Acid Receptor beta antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- Specific for the ~48k RAR-( isotype.
- 交叉反应
- 人, 大鼠
- 预测反应
- canine, guinea pig, mouse, non-human primate
- 纯化方法
- Protein G purified culture supernatant
- 免疫原
- Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH
- 克隆位点
- 336
- 亚型
- IgG1
- Top Product
- Discover our top product RARB Primary Antibody
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- 应用备注
- Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
- 储存条件
- -20 °C
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- 抗原
- Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))
- 别名
- RARB (RARB 产品)
- 别名
- RARB antibody, nRARs antibody, HAP antibody, NR1B2 antibody, RRB2 antibody, A830025K23 antibody, Hap antibody, Nr1b2 antibody, RARbeta2 antibody, RARBETA antibody, retinoic acid receptor beta antibody, retinoic acid receptor, beta antibody, RARB antibody, Rarb antibody
- 背景
- Retinoic Acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X receptors (RXRs) family (RXRa, ß and () preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors (RARs). RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005). Anti- Retinoic Acid Receptor, (-Isotype Western blot of hippocampal lysate showing specific immunolabeling of the ~48k RAR-ß isotype.
- 分子量
- '48 kDa
- 基因ID
- 5915
- UniProt
- P10826
- 途径
- Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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