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NEFM 抗体 (C-Term)

NEFM 适用: 大鼠 WB, IF 宿主: 小鸡 Polyclonal unconjugated
产品编号 ABIN361355
发货至: 中国
  • 抗原 See all NEFM 抗体
    NEFM (Neurofilament Triplet M Protein (NEFM))
    抗原表位
    • 16
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 61
    • 43
    • 35
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    • 6
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    • 2
    • 1
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    大鼠
    宿主
    • 41
    • 23
    • 10
    • 1
    小鸡
    克隆类型
    • 43
    • 32
    多克隆
    标记
    • 47
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    This NEFM antibody is un-conjugated
    应用范围
    • 61
    • 22
    • 21
    • 17
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    • 5
    • 2
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    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    Specific for the ~145k Neurofilament M protein.
    交叉反应
    小鸡, 牛, 人, 小鼠, 大鼠
    纯化方法
    Total IgY fraction
    免疫原
    Preparation containing the extreme C-terminus expressed in and purified from E. Coli
    Top Product
    Discover our top product NEFM Primary Antibody
  • 应用备注
    Recommended Dilution: WB: 1:5,000 IF: 1:1000 Quality Control: Western blots performed on each lot.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    total IgY fraction in PBS + 10 mM Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • Glass, Kelm-Nelson, Szot, Lake, Connor, Ciucci: "Functional characterization of extrinsic tongue muscles in the Pink1-/- rat model of Parkinson disease." in: PloS one, Vol. 15, Issue 10, pp. e0240366, (2020) (PubMed).

  • 抗原
    NEFM (Neurofilament Triplet M Protein (NEFM))
    别名
    NEFM (NEFM 产品)
    背景
    Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-M is the neurofilament middle or medium molecular weight polypeptide and runs on SDS-PAGE gels at 145-160 kDa, with some variability across species boundaries. Antibodies to NF-M are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-M antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) and Alzheimer's disease (2). Anti-Neurofilament M Western blot of rat cortex lysate showing specific immunolableing of the ~ 145k NF-M protein.
    分子量
    '145 kDa
    基因ID
    24588
    UniProt
    P12839
    途径
    Brown Fat Cell Differentiation
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