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- 抗原 See all NEFH 抗体
- NEFH (Neurofilament, Heavy Polypeptide (NEFH))
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适用
- Cow
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宿主
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小鸡
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克隆类型
- 多克隆
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标记
- This NEFH antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 特异性
- Specific for the ~200k Neurofilament H protein.
- 交叉反应
- 小鸡, 哺乳动物
- 纯化方法
- Total IgY fraction
- 免疫原
- Purified bovine NF-H
- Top Product
- Discover our top product NEFH Primary Antibody
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- 应用备注
- Recommended Dilution: WB: 1:50,000 IF: 1:25,000 Quality Control: Western blots performed on each lot.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- total IgY fraction in PBS + 10 mM Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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SHANK3 deficiency leads to myelin defects in the central and peripheral nervous system." in: Cellular and molecular life sciences : CMLS, Vol. 79, Issue 7, pp. 371, (2022) (PubMed).
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SHANK3 deficiency leads to myelin defects in the central and peripheral nervous system." in: Cellular and molecular life sciences : CMLS, Vol. 79, Issue 7, pp. 371, (2022) (PubMed).
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- 抗原
- NEFH (Neurofilament, Heavy Polypeptide (NEFH))
- 别名
- NEFH (NEFH 产品)
- 别名
- NF-H antibody, NF200 antibody, Nfh antibody, mKIAA0845 antibody, NFH antibody, NEFH antibody, neurofilament heavy polypeptide antibody, neurofilament, heavy polypeptide antibody, neurofilament heavy antibody, MCYG_06231 antibody, Nefh antibody, NEFH antibody
- 背景
- Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-H is the neurofilament high or heavy molecular weight polypeptide and runs on SDS-PAGE gels at 200-220 kDa, with some variability across species boundaries. Antibodies to NF-H are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-H antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) (2) and Alzheimer's disease (3). Anti-Neurofilament H Left: Western blot of rat cortex lysate showing specific immunolableing of the ~200k NF-H protein. Right: Immunofluorescence of rat cortical neurons and glia showing NF-H staining (red).
- 分子量
- '200 kDa
- 基因ID
- 4744
- UniProt
- P12036
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