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NEFH 抗体

NEFH 适用: Cow WB, IF 宿主: 小鼠 Monoclonal NAP4 unconjugated
产品编号 ABIN361350
发货至: 中国
  • 抗原 See all NEFH 抗体
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    适用
    • 114
    • 83
    • 64
    • 50
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    • 22
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    • 9
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    Cow
    宿主
    • 67
    • 57
    • 8
    小鼠
    克隆类型
    • 82
    • 50
    单克隆
    标记
    • 83
    • 5
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    This NEFH antibody is un-conjugated
    应用范围
    • 81
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    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    Specific for the ~200k Neurofilament H protein. It recognizes phosphorylated NF-H KSP (lysine-serine-proline) type sequences. In some species there is some cross-reactivity with the related phosphorylated KSP sequences found in the related neurofilament subunit NF-M. It recognizes neurofilaments in frozen sections in tissue culture and in formalin fixed sections.
    交叉反应
    小鸡, 哺乳动物
    纯化方法
    Protein G purified culture supernatant
    免疫原
    Purified bovine NF-H
    克隆位点
    NAP4
    亚型
    IgG1
    Top Product
    Discover our top product NEFH Primary Antibody
  • 应用备注
    Recommended Dilution: WB: 1:5,000 IF: 1:500 Quality Control: Western blots performed on each lot.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    total IgG fraction + 10 mM Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    别名
    NEFH (NEFH 产品)
    背景
    Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-H is the neurofilament high or heavy molecular weight polypeptide and runs on SDS-PAGE gels at 200-220 kDa, with some variability across species boundaries. Antibodies to NF-H are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-H antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) (2) and Alzheimer's disease (3). Anti-Neurofilament H Western blot of rat cortex lysate showing specific immunolableing of the ~ 200k NF-H protein.
    分子量
    '200 kDa
    基因ID
    4744
    UniProt
    P12036
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