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NEFH 抗体

NEFH 适用: Cow WB, IF 宿主: 小鼠 Monoclonal NAP4 unconjugated
产品编号 ABIN361350
发货至: 中国
  • 抗原 See all NEFH 抗体
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    适用
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    • 82
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    Cow
    宿主
    • 66
    • 56
    • 8
    小鼠
    克隆类型
    • 80
    • 50
    单克隆
    标记
    • 81
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    This NEFH antibody is un-conjugated
    应用范围
    • 83
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    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    Specific for the ~200k Neurofilament H protein. It recognizes phosphorylated NF-H KSP (lysine-serine-proline) type sequences. In some species there is some cross-reactivity with the related phosphorylated KSP sequences found in the related neurofilament subunit NF-M. It recognizes neurofilaments in frozen sections in tissue culture and in formalin fixed sections.
    交叉反应
    小鸡, 哺乳动物
    纯化方法
    Protein G purified culture supernatant
    免疫原
    Purified bovine NF-H
    克隆位点
    NAP4
    亚型
    IgG1
    Top Product
    Discover our top product NEFH Primary Antibody
  • 应用备注
    Recommended Dilution: WB: 1:5,000 IF: 1:500 Quality Control: Western blots performed on each lot.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    total IgG fraction + 10 mM Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    别名
    NEFH (NEFH 产品)
    别名
    NF-H antibody, NF200 antibody, Nfh antibody, mKIAA0845 antibody, NFH antibody, NEFH antibody, neurofilament heavy polypeptide antibody, neurofilament, heavy polypeptide antibody, neurofilament heavy antibody, MCYG_06231 antibody, Nefh antibody, NEFH antibody
    背景
    Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-H is the neurofilament high or heavy molecular weight polypeptide and runs on SDS-PAGE gels at 200-220 kDa, with some variability across species boundaries. Antibodies to NF-H are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. NF-H antibodies can also be useful to visualize neurofilament accumulations seen in many neurological diseases, such as Amyotrophic Lateral Sclerosis (Lou Gehrig's disease) (2) and Alzheimer's disease (3). Anti-Neurofilament H Western blot of rat cortex lysate showing specific immunolableing of the ~ 200k NF-H protein.
    分子量
    '200 kDa
    基因ID
    4744
    UniProt
    P12036
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