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DUSP4 抗体 (C-Term)

DUSP4 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN360778
发货至: 中国
  • 抗原 See all DUSP4 抗体
    DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
    抗原表位
    • 16
    • 8
    • 7
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 56
    • 39
    • 9
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 52
    • 4
    克隆类型
    • 52
    • 4
    多克隆
    标记
    • 23
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DUSP4 antibody is un-conjugated
    应用范围
    • 43
    • 24
    • 20
    • 14
    • 13
    • 13
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to DUSP4.
    纯化方法
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human DUSP4.
    亚型
    Ig Fraction
    Top Product
    Discover our top product DUSP4 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    DUSP4 (Dual Specificity Phosphatase 4 (DUSP4))
    别名
    DUSP4 (DUSP4 产品)
    别名
    zgc:55423 antibody, DUSP4 antibody, typ antibody, hvh2 antibody, mkp2 antibody, mkp-2 antibody, MGC131045 antibody, HVH2 antibody, MKP-2 antibody, MKP2 antibody, TYP antibody, 2700078F24Rik antibody, AI844617 antibody, BB104621 antibody, E130306H24Rik antibody, Mkp-2 antibody, Mkp2 antibody, dual specificity phosphatase 4 antibody, dual specificity phosphatase 4 S homeolog antibody, dusp4 antibody, DUSP4 antibody, dusp4.S antibody, Dusp4 antibody
    背景
    DUSP4 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP4 inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus.Synonyms: Dual specificity protein phosphatase 4, Dual specificity protein phosphatase hVH2, MKP2, Mitogen-activated protein kinase phosphatase 2, VH2
    基因ID
    1846, 9606
    UniProt
    Q13115
    途径
    Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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