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PHLPP2 抗体 (N-Term)

PHLPP2 适用: 人 IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN360110
发货至: 中国
  • 抗原 See all PHLPP2 抗体
    PHLPP2 (PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2))
    抗原表位
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    适用
    • 16
    • 5
    • 2
    • 1
    • 1
    宿主
    • 15
    • 1
    克隆类型
    • 16
    多克隆
    标记
    • 16
    This PHLPP2 antibody is un-conjugated
    应用范围
    • 16
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to PHLPP2.
    纯化方法
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-term region of human PHLPP2.
    亚型
    Ig Fraction
    Top Product
    Discover our top product PHLPP2 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Immunohistochemistry: 1/10 - 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    PHLPP2 (PH Domain and Leucine Rich Repeat Protein Phosphatase 2 (PHLPP2))
    别名
    PHLPP2 (PHLPP2 产品)
    别名
    PHLPPL antibody, phlppl antibody, AI481772 antibody, C130044A18Rik antibody, Phlppl antibody, RGD1562857 antibody, PH domain and leucine rich repeat protein phosphatase 2 antibody, PH domain and leucine rich repeat protein phosphatase 2 S homeolog antibody, PHLPP2 antibody, phlpp2.S antibody, phlpp2 antibody, Phlpp2 antibody
    背景
    PHLPP2 is a protein phosphatase that specifically mediates dephosphorylation of 'Ser-473' of AKT1. This protein regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decrease cell proliferation. It also controls the phosphorylation of AKT3.Synonyms: KIAA0931, PH domain leucine-rich repeat-containing protein phosphatase 2, PH domain leucine-rich repeat-containing protein phosphatase-like, PHLPP-like, PHLPPL
    基因ID
    23035, 9606
    UniProt
    Q6ZVD8
    途径
    PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway
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