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BLK 抗体 (N-Term)

Name: BLK 抗体 (N-Term)
SKU: ABIN359972
Availability: OutOfStock

BLK 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

Image no. 2 for anti-B Lymphoid Tyrosine Kinase (BLK) (N-Term) antibody (ABIN359972) (BLK 抗体 (N-Term))

Image no. 1 for anti-B Lymphoid Tyrosine Kinase (BLK) (N-Term) antibody (ABIN359972) (BLK 抗体 (N-Term))

2 images

(1 reference)

产品编号 ABIN359972

发货至: 中国

Datasheet as PDF

抗原 See all BLK 抗体

BLK (B Lymphoid Tyrosine Kinase (BLK))
抗原表位
15

13

8

7

4

4

3

2

2

2

1

1

1

1

1

1

1
N-Term
适用
66

23

15

2

1

1

1

1

1

1

1
人, 小鼠
宿主
53

10

1
兔
Compatible Secondaries
克隆类型
55

11
多克隆
标记
35

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This BLK antibody is un-conjugated
应用范围
51

38

29

13

13

7

4

3

2

2

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

特异性

This antibody reacts to BLK.

纯化方法

Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

免疫原

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human BLK.

亚型

Ig Fraction

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anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-90) antibody
BLK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7A12 unconjugated

anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-505) antibody
BLK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E5-3A8 unconjugated

anti-B Lymphoid Tyrosine Kinase (BLK) antibody
BLK 适用: 人 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 1-00E-06 unconjugated

anti-B Lymphoid Tyrosine Kinase (BLK) antibody
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BLK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB03107 unconjugated

anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-280) antibody
BLK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-505) antibody
BLK 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-B Lymphoid Tyrosine Kinase (BLK) antibody
BLK 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 9D10D1 unconjugated

anti-B Lymphoid Tyrosine Kinase (BLK) (AA 1-280) antibody
BLK 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

应用备注

ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

浓度

0.25 mg/mL

缓冲液

PBS with 0.09 % (W/V) sodium azide

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Borowiec, Liew, Thompson, Boonyasrisawat, Hu, Mlynarski, El Khattabi, Kim, Marselli, Rich, Krolewski, Bonner-Weir, Sharma, Sale, Mychaleckyj, Kulkarni, Doria: "Mutations at the BLK locus linked to maturity onset diabetes of the young and beta-cell dysfunction." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 34, pp. 14460-5, (2009) (PubMed).
抗原

BLK (B Lymphoid Tyrosine Kinase (BLK))

别名

BLK (BLK 产品)

别名

bltk antibody, si:dkey-33i22.2 antibody, zgc:136231 antibody, MODY11 antibody, BLK proto-oncogene, Src family tyrosine kinase antibody, B lymphoid kinase antibody, blk antibody, BLK antibody, Blk antibody

背景

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.Synonyms: B lymphocyte kinase, Tyrosine-protein kinase BLK, p55-BLK, p55BLK

基因ID

640, 9606

UniProt

P51451

途径

Positive Regulation of Peptide Hormone Secretion, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling