DDR1 抗体 (N-Term)
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- 抗原 See all DDR1 抗体
- DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DDR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to DDR1.
- 纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- 免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MCK10.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product DDR1 Primary Antibody
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anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 299-330) antibody
DDR1 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 568-829) antibodyDDR1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 21-176) antibodyDDR1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4F2C12 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 299-330) antibodyDDR1 适用: 人 WB, IHC (p), FACS, IF 宿主: 兔 Polyclonal RB14442 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 17-47), (N-Term) antibodyDDR1 适用: 人, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB01477 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 17-47) antibodyDDR1 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 21-120) antibodyDDR1 适用: 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 396-430) antibodyDDR1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB50593 unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (AA 22-876) antibodyDDR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Discoidin Domain Receptor tyrosine Kinase 1 (DDR1) (C-Term) antibodyDDR1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
- 别名
- CD167a / DDR1 (DDR1 产品)
- 背景
- Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. MCK10 is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain. The gene is located on chromosome 6p21.3 in proximity to several HLA class I genes.Synonyms: CAK, CD167 antigen-like family member A, EDDR1, Epithelial discoidin domain receptor 1, Epithelial discoidin domain-containing receptor 1, MCK10, NEP, NTRK4, PTK3A, RTK6, TRKE, Tyrosine kinase DDR-1
- 基因ID
- 780, 9606
- UniProt
- Q08345
- 途径
- RTK signaling, Smooth Muscle Cell Migration
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