Ketohexokinase 抗体 (C-Term)
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- 抗原 See all Ketohexokinase (KHK) 抗体
- Ketohexokinase (KHK)
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抗原表位
- C-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Ketohexokinase antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to Ketohexokinase (KHK).
- 纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- 免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human KHK.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product KHK Primary Antibody
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- 应用备注
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Flow cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- Ketohexokinase (KHK)
- 别名
- Ketohexokinase (KHK 产品)
- 别名
- wu:fj68h03 antibody, zgc:92219 antibody, zgc:92626 antibody, KHK antibody, khk antibody, KETHPRO antibody, ketohexokinase antibody, Ketohexokinase antibody, KHK antibody, khk antibody, Hhal_0921 antibody, AaeL_AAEL006316 antibody, Nwat_0240 antibody, Khk antibody
- 背景
- Ketohexokinase (KHK), or fructokinase, catalyzes conversion of fructose to fructose-1-phosphate. Splice variant 1 is the highly active form found in liver, renal cortex, and small intestine, while splice variant 2 is the lower activity form found in most other tissues. KHK, like glucokinase (GCK) and glucokinase regulator (GCKR), is present in both liver and pancreatic islets. The inhibition of GCK by GCKR is blocked by binding of fructose-1-phosphate to GCKR. The chromosomal proximity of the metabolically connected GCKR and KHK genes has a genetic linkage in type 2 diabetes. Fructosuria, or hepatic fructokinase deficiency, is a benign, asymptomatic defect of intermediary metabolism associated with heterozygosity for G50R and A43T mutations in KHK.Synonyms: EC=2.7.1.3, Hepatic fructokinase, KHK, Ketohexokinase
- 基因ID
- 3795, 9606
- UniProt
- P50053
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