PRKAR1B 抗体 (N-Term)
-
- 抗原 See all PRKAR1B 抗体
- PRKAR1B (Protein Kinase, CAMP-Dependent, Regulatory, Type I, beta (PRKAR1B))
-
抗原表位
- N-Term
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PRKAR1B antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody reacts to PKA R1 beta (PRKAR1B).
- 纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- 免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PRKAR1B.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product PRKAR1B Primary Antibody
-
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type I, beta (PRKAR1B) antibody
PRKAR1B 适用: 人 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 2A3 unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type I, beta (PRKAR1B) antibodyPRKAR1B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type I, beta (PRKAR1B) (AA 1-90) antibodyPRKAR1B 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1F8 unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type I, beta (PRKAR1B) (Internal Region) antibodyPRKAR1B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type I, beta (PRKAR1B) (AA 1-381) antibodyPRKAR1B 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type I, beta (PRKAR1B) (AA 190-290), (Regulatory Subunit) antibodyPRKAR1B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type I, beta (PRKAR1B) (AA 190-290), (Regulatory Subunit) antibodyPRKAR1B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type I, beta (PRKAR1B) (C-Term) antibodyPRKAR1B 适用: 人, 小鼠, 大鼠, 犬, 斑马鱼, 小鸡, Cow, 豚鼠, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type I, beta (PRKAR1B) (AA 1-381) antibodyPRKAR1B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase, CAMP-Dependent, Regulatory, Type I, beta (PRKAR1B) (AA 106-155) antibodyPRKAR1B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
-
- 抗原
- PRKAR1B (Protein Kinase, CAMP-Dependent, Regulatory, Type I, beta (PRKAR1B))
- 别名
- PRKAR1B (PRKAR1B 产品)
- 别名
- PRKAR1B antibody, AI385716 antibody, RIbeta antibody, RGD1563094 antibody, PRKAR1 antibody, zgc:153624 antibody, prkar1 antibody, protein kinase cAMP-dependent type I regulatory subunit beta antibody, protein kinase, cAMP dependent regulatory, type I beta antibody, protein kinase cAMP-dependent type 1 regulatory subunit beta antibody, protein kinase, cAMP-dependent, regulatory, type I, beta antibody, protein kinase, cAMP-dependent, regulatory subunit type I beta S homeolog antibody, PRKAR1B antibody, prkar1b antibody, Prkar1b antibody, prkar1b.S antibody
- 背景
- The second messenger cyclic AMP (cAMP) mediates diverse cellular responses to external signals such as proliferation, ion transport, regulation of metabolism and gene transcription by activation of the cAMP-dependent protein kinase (cAPK or PKA). Activation of PKA occurs when cAMP binds to the two regulatory subunits of the tetrameric PKA holoenzyme resulting in release of active catalytic subunits. Three catalytic (C) subunits have been identified, designated Cα, Cβ and Cγ, that each represent specific gene products. Cα and Cβ are closely related (93 % amino acid sequence similarity), whereas Cγ displays 83 % and 79 % similarity to Cα and Cβ, respectively. Activation of transcription upon elevation of cAMP levels results from translocation of PKA to the nucleus where it phosphorylates the transcription factor cAMP response element binding protein (CREB) on serine 133 which in turn leads to TFIIB binding to TATA-box-binding protein TBP1, thus linking phospho-CREB to the pol II transcription initiation complex.Synonyms: PKA regulatory subunit I beta, PRKAR1, cAMP-dependent protein kinase type I-beta regulatory subunit
- 基因ID
- 5575, 9606
- UniProt
- P31321
- 途径
- Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
-
