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TEK 抗体 (pTyr1113)

TEK 适用: 人 EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN358489
发货至: 中国
  • 抗原 See all TEK 抗体
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    抗原表位
    • 20
    • 19
    • 16
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr1113
    适用
    • 124
    • 62
    • 47
    • 22
    • 4
    • 3
    宿主
    • 116
    • 18
    • 4
    • 3
    • 2
    克隆类型
    • 122
    • 21
    多克隆
    标记
    • 72
    • 10
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TEK antibody is un-conjugated
    应用范围
    • 77
    • 57
    • 40
    • 40
    • 30
    • 30
    • 13
    • 13
    • 12
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    Enzyme Immunoassay (EIA)
    特异性
    This antibody detects TEK pTyr1113. Predicted to cross react with Mouse and Zebrafish (100 % Antigen Homology).
    纯化方法
    Protein A Chromatography followed by two-step phosphospecific peptide affinity purification.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1113 of human TEK.
    亚型
    Ig Fraction
    Top Product
    Discover our top product TEK Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Dot Blot: 1/500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    TEK (TEK Tyrosine Kinase, Endothelial (TEK))
    别名
    CD202b / TEK (TEK 产品)
    背景
    The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.Synonyms: Angiopoietin-1 receptor, TIE-2, TIE2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK
    分子量
    125810 Da
    基因ID
    83659, 9606
    UniProt
    Q02763
    途径
    RTK signaling, Growth Factor Binding
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