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FNTB 抗体 (N-Term)

FNTB 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN357706
发货至: 中国
  • 抗原 See all FNTB 抗体
    FNTB (Farnesyltransferase subunit beta (FNTB))
    抗原表位
    • 8
    • 8
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 54
    • 22
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 53
    • 1
    克隆类型
    • 43
    • 11
    多克隆
    标记
    • 21
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This FNTB antibody is un-conjugated
    应用范围
    • 34
    • 28
    • 13
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody is specific to FNTB (N-term).
    纯化方法
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human FNTB.
    亚型
    Ig Fraction
    Top Product
    Discover our top product FNTB Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    FNTB (Farnesyltransferase subunit beta (FNTB))
    别名
    FNTB (FNTB 产品)
    别名
    FPTB antibody, 2010013E13Rik antibody, AA409500 antibody, farnesyltransferase, CAAX box, beta antibody, FNTB antibody, Fntb antibody
    背景
    Eukaryotic cells contain 3 different types of prenyltransferases that attach either a farnesyl group (15 carbons) or a geranylgeranyl group (20 carbons) in thioether linkage to C-terminal cysteine residues in a variety of proteins. These posttranslational modifications provide a mechanism for membrane localization of proteins that lack a transmembrane domain. CAAX farnesyltransferase (FTase) attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the CAAX box, where C is cysteine, A is usually but not always an aliphatic amino acid, and X is typically methionine or serine. This enzyme has the ability to farnesylate peptides as short as 4 residues in length that conform to the CAAX consensus sequence. The gene for the beta subunit of CAAX farnesyltransferase (FNTB) has been pinpointed to 14q23-q24 by Southern blot hybridization and PCR analyses of panels of human/Chinese hamster somatic cell hybrid lines and by fluorescence chromosomal in situ hybridization.Synonyms: CAAX farnesyltransferase subunit beta, FTase-beta, Protein farnesyltransferase subunit beta, Ras proteins prenyltransferase subunit beta
    分子量
    58521 Da
    基因ID
    2342, 9606
    UniProt
    P49356
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