MIB1 抗体 (N-Term)
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- 抗原 See all MIB1 抗体
- MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MIB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody is specific to MIB1 (N-term). Predicted to cross react with Mouse and Zebrafish (100 % Antigen Homology).
- 纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- 免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MIB.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product MIB1 Primary Antibody
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anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 6-221) antibody
MIB1 适用: 人 ELISA, WB, FACS 宿主: 小鼠 Monoclonal 2A7B1 unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 5-332) antibodyMIB1 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (Internal Region) antibodyMIB1 适用: 人, 小鼠, 大鼠, Cow, 犬 ELISA, WB, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 13-42), (N-Term) antibodyMIB1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB4448 unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 901-950) antibodyMIB1 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 769-1000) antibodyMIB1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 909-1006) antibodyMIB1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 909-1006) antibodyMIB1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3E10 unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (AA 560-860) antibodyMIB1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1) (C-Term) antibodyMIB1 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100. Immunofluorescence: 1/20-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
- 别名
- MIB1 (MIB1 产品)
- 别名
- DIP-1 antibody, DIP1 antibody, LVNC7 antibody, MIB antibody, ZZANK2 antibody, ZZZ6 antibody, E430019M12Rik antibody, Mib antibody, mKIAA1323 antibody, dip-1 antibody, mib antibody, mindbomb antibody, cg5841 antibody, chunp6889 antibody, fe47f05 antibody, im:7148100 antibody, mib1 antibody, wu:fe47f05 antibody, CG5841 antibody, D-mib antibody, D-mib1 antibody, Dmel\CG5841 antibody, Dmib antibody, MIB1 antibody, Mib1 antibody, dmib1 antibody, l(3)72CDa antibody, l(3)72Db antibody, mib1/2 antibody, mind-bomb antibody, mindbomb E3 ubiquitin protein ligase 1 antibody, mindbomb E3 ubiquitin protein ligase 1 L homeolog antibody, mind bomb 1 antibody, MIB1 antibody, Mib1 antibody, mib1.L antibody, mib1 antibody
- 背景
- MIB is an E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. This protein positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. MIB probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.Synonyms: DAPK-interacting protein 1, DIP1, E3 ubiquitin-protein ligase MIB1, KIAA1323, Mind bomb homolog 1, ZZANK2, Zinc finger ZZ type with ankyrin repeat domain protein 2
- 分子量
- 110135 Da
- 基因ID
- 57534, 9606
- UniProt
- Q86YT6
- 途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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