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USP13 抗体 (Middle Region)

USP13 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN357545
发货至: 中国
  • 抗原 See all USP13 抗体
    USP13 (Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13))
    抗原表位
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 51
    • 32
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 小鼠
    宿主
    • 50
    • 4
    克隆类型
    • 43
    • 11
    多克隆
    标记
    • 30
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This USP13 antibody is un-conjugated
    应用范围
    • 39
    • 23
    • 20
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody is specific to USP13 (Center).
    纯化方法
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human USP13.
    亚型
    Ig Fraction
    Top Product
    Discover our top product USP13 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    USP13 (Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13))
    别名
    USP13 (USP13 产品)
    别名
    ISOT3 antibody, IsoT-3 antibody, 2700071E21Rik antibody, AI848077 antibody, usp13 antibody, MGC163140 antibody, ubiquitin specific peptidase 13 antibody, ubiquitin specific peptidase 13 (isopeptidase T-3) antibody, ubiquitin carboxyl-terminal hydrolase 13 antibody, universal stress protein antibody, USP13 antibody, Usp13 antibody, usp13 antibody, MGYG_01656 antibody, RR_RS02895 antibody
    背景
    Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.Synonyms: Deubiquitinating enzyme 13, ISOT-3, ISOT3, Isopeptidase T-3, Ubiquitin carboxyl-terminal hydrolase 13, Ubiquitin thioesterase 13, Ubiquitin-specific-processing protease 13
    分子量
    97299 Da
    基因ID
    8975, 5874
    UniProt
    Q92995
    途径
    SARS-CoV-2 Protein Interactome
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