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- 抗原 See all SLUG (SNAI2) 抗体
- SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
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抗原表位
- N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLUG antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects SLUG at N-term.
- 纯化方法
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- 免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SLUG.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product SNAI2 Primary Antibody
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- 应用备注
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ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS with 0.09 % (W/V) sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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miR-33a suppresses the nuclear translocation of ?-catenin to enhance gemcitabine sensitivity in human pancreatic cancer cells." in: Tumour biology, (2015) (PubMed).
: "Hepatocyte growth factor activates Wnt pathway by transcriptional activation of LEF1 to facilitate tumor invasion." in: Carcinogenesis, Vol. 33, Issue 6, pp. 1142-8, (2012) (PubMed).
: "The postnatal accumulation of junctional E-cadherin is inversely correlated with the capacity for supporting cells to convert directly into sensory hair cells in mammalian balance organs." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 33, pp. 11855-66, (2011) (PubMed).
: "Ubiquitin ligase cullin 7 induces epithelial-mesenchymal transition in human choriocarcinoma cells." in: The Journal of biological chemistry, Vol. 285, Issue 14, pp. 10870-9, (2010) (PubMed).
: "The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling." in: Human molecular genetics, Vol. 16, Issue 1, pp. 92-106, (2007) (PubMed).
: "Hepatic lipid accumulation in apolipoprotein C-I-deficient mice is potentiated by cholesteryl ester transfer protein." in: Journal of lipid research, Vol. 48, Issue 1, pp. 30-40, (2006) (PubMed).
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miR-33a suppresses the nuclear translocation of ?-catenin to enhance gemcitabine sensitivity in human pancreatic cancer cells." in: Tumour biology, (2015) (PubMed).
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- 抗原
- SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
- 别名
- SNAI2 / SLUG (SNAI2 产品)
- 背景
- SLUG is a member of the Snail family of C2H2-type zinc finger transcription factors. This protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in the gene encoding SLUG may be associated with sporadic cases of neural tube defects.Synonyms: Neural crest transcription factor Slug, Protein snail homolog 2, SLUGH, Zinc finger protein SNAI2
- 分子量
- 29986 Da
- 基因ID
- 6591, 9606
- UniProt
- O43623
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