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PROX1 抗体 (Center)

Name: PROX1 抗体 (Center)
SKU: ABIN357418
Availability: OutOfStock

PROX1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

Image no. 2 for anti-Prospero Homeobox 1 (PROX1) (Center) antibody (ABIN357418) (PROX1 抗体 (Center))

Image no. 1 for anti-Prospero Homeobox 1 (PROX1) (Center) antibody (ABIN357418) (PROX1 抗体 (Center))

Image no. 3 for anti-Prospero Homeobox 1 (PROX1) (Center) antibody (ABIN357418) (PROX1 抗体 (Center))

3 images

(2 references)

产品编号 ABIN357418

发货至: 中国

Datasheet as PDF

抗原 See all PROX1 抗体

PROX1 (Prospero Homeobox 1 (PROX1))
抗原表位
16

14

9

9

8

8

6

5

4

3

2

2

2

2

1

1

1

1

1
Center
适用
99

52

26

3

2

2

1

1

1

1

1

1

1

1
人, 小鼠
宿主
91

8
兔
Compatible Secondaries
克隆类型
90

9
多克隆
标记
47

9

8

7

6

5

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This PROX1 antibody is un-conjugated
应用范围
81

47

36

28

13

13

11

3

2

2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

特异性

This antibody detects PROX1 at Center.

纯化方法

Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Then the antibody is purified by peptide affinity purification.

免疫原

KLH conjugated synthetic peptide selected from the Center region of human PROX1

亚型

Ig Fraction

Top Product

Discover our top product PROX1 Primary Antibody
anti-Prospero Homeobox 1 (PROX1) (AA 638-737) antibody
PROX1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 492-520) antibody
PROX1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 492-522) antibody
PROX1 适用: 人, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 185-214) antibody
PROX1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 638-737) antibody
PROX1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E7 unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 444-478) antibody
PROX1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB51404 unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 1-300) antibody
PROX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 547-737) antibody
PROX1 适用: 人, 马, Avian WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Prospero Homeobox 1 (PROX1) antibody
PROX1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 185-214) antibody
PROX1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB13371 unconjugated

应用备注

ELISA: 1/1,000. Western blot: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

浓度

0.25 mg/mL

缓冲液

PBS with 0.09 % (W/V) sodium azide

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Park, Cho, Park, Kim, Park, Myung, Lee, Kweon, Joo: "Prospero homeobox 1 mediates the progression of gastric cancer by inducing tumor cell proliferation and lymphangiogenesis." in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, Vol. 20, Issue 1, pp. 104-115, (2017) (PubMed).

Park, Myung, Park, Kim, Oak, Myung, Cho, Lee, Kweon, Kim, Joo: "Impact of prospero homeobox-1 on tumor cell behavior and prognosis in colorectal cancer." in: American journal of cancer research, Vol. 5, Issue 11, pp. 3286-300, (2016) (PubMed).
抗原

PROX1 (Prospero Homeobox 1 (PROX1))

别名

PROX-1 (PROX1 产品)

别名

xprox1 antibody, prospero antibody, PROX1 antibody, LOC100232600 antibody, A230003G05Rik antibody, prox1 antibody, zgc:111888 antibody, prospero homeobox 1 antibody, prospero homeobox 1 L homeolog antibody, prospero homeobox 1a antibody, PROX1 antibody, prox1.L antibody, prox1 antibody, Prox1 antibody, prox1a antibody

背景

The expression pattern of Prox1 suggests that it has a role in a variety of embryonic tissues, including lens. Prox mRNA is present in many different human tissues with lens demonstrating the highest level. Homozygous Prox1-null mice die at midgestation from multiple developmental defects, and a targeted effect on lens development has been reported. Prox1 inactivation caused abnormal cellular proliferation, downregulated expression of the cell cycle inhibitors Cdkn1b and Cdkn1c, misexpression of E-cadherin, and excessive apoptosis. Consequently, mutant lens cells failed to polarize and elongate properly, resulting in a hollow lens. Prox1 is expressed in a subpopulation of endothelial cells that by budding and sprouting give rise to the lymphatic system. Prox1 appears to be a specific and required regulator of the development of the lymphatic system. Prox1 also has been documented to be required for hepatocyte migration in the mouse. Loss of Prox1 results in a smaller liver with a reduced population of clustered hepatocytes. The homeodomain protein Prox1 regulates the egress of progenitor cells from the cell cycle in the embryonic mouse retina. Cells lacking Prox1 are less likely to stop dividing, and ectopic expression of Prox1 forces progenitor cells to exit the cell cycle. Prox1 acts as a key participant in progenitor-cell proliferation and cell-fate determination in the vertebrate retina.Synonyms: Homeobox prospero-like protein PROX1, PROX1, Prospero homeobox protein 1

分子量

83162 Da

基因ID

5629, 9606

UniProt

Q92786

途径

Stem Cell Maintenance, Regulation of Muscle Cell Differentiation