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DKK3 抗体 (N-Term)

适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN357071
发货至: 中国
  • 抗原 See all DKK3 抗体
    DKK3
    抗原表位
    • 15
    • 9
    • 9
    • 8
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 54
    • 35
    • 17
    • 14
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 66
    • 5
    • 2
    • 1
    克隆类型
    • 67
    • 7
    多克隆
    标记
    • 33
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DKK3 antibody is un-conjugated
    应用范围
    • 54
    • 38
    • 29
    • 13
    • 13
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects DKK3 at N-term.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Protein G Chromatography eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human DKK3.
    亚型
    Ig Fraction
    Top Product
    Discover our top product DKK3 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    DKK3
    别名
    Dickkopf-3 (DKK3) (DKK3 产品)
    别名
    REIC antibody, RIG antibody, reic antibody, dkk-3 antibody, AW061014 antibody, C87148 antibody, Reic antibody, p29 antibody, dickkopf WNT signaling pathway inhibitor 3 antibody, dickkopf WNT signaling pathway inhibitor 3 S homeolog antibody, DKK3 antibody, dkk3 antibody, dkk3.S antibody, Dkk3 antibody
    背景
    DKK3, like DKK1, DKK2, and DKK4, possesses an N-terminal signal peptide and 2 conserved cysteine-rich domains, which are separated by a linker region and contain 10 cysteine residues each. The second cysteine region has a putative lipid-binding function that may facilitate WNT/DKK interactions at the plasma membrane. The linker region contains 50 to 55 amino acids in DKK1, DKK2, and DKK4, whereas in DKK3 it contains only 12 amino acids. All DKKs have several potential sites for cleavage by furin-type proteases. Northern blot analysis revealed wide expression of the DKK3 transcript, with highest expression in heart, brain, and spinal cord. In situ hybridization reveals highest expression in mouse brain, eye, and heart.Synonyms: Dickkopf-related protein 3, Dkk-3, REIC
    分子量
    38291 Da
    基因ID
    27122
    NCBI登录号
    NP_001018067
    UniProt
    Q9UBP4
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