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TLR1 抗体 (C-Term)

Name: TLR1 抗体 (C-Term)
SKU: ABIN357041
Availability: OutOfStock

TLR1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

Image no. 2 for anti-Toll-Like Receptor 1 (TLR1) (C-Term) antibody (ABIN357041) (TLR1 抗体 (C-Term))

Image no. 1 for anti-Toll-Like Receptor 1 (TLR1) (C-Term) antibody (ABIN357041) (TLR1 抗体 (C-Term))

2 images

产品编号 ABIN357041

发货至: 中国

Datasheet as PDF

抗原 See all TLR1 抗体

TLR1 (Toll-Like Receptor 1 (TLR1))
抗原表位
16

9

8

5

4

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
C-Term
适用
73

45

26

3

3

1
人, 小鼠
宿主
73

13

2
兔
Compatible Secondaries
克隆类型
76

12
多克隆
标记
31

13

9

7

4

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This TLR1 antibody is un-conjugated
应用范围
62

33

32

29

13

13

10

8

8

6

6

4

2

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

特异性

This antibody detects TLR1 at C-term.

纯化方法

Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

免疫原

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of Mouse TLR1.

亚型

Ig Fraction

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anti-Toll-Like Receptor 1 (TLR1) (AA 101-200) antibody
TLR1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 1 (TLR1) (AA 114-339) antibody
TLR1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 8-3# unconjugated

anti-Toll-Like Receptor 1 (TLR1) (AA 350-404) antibody
TLR1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, ICC 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 1 (TLR1) (AA 25-580) antibody
TLR1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 1 (TLR1) (AA 25-134) antibody
TLR1 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 1 (TLR1) antibody (PE-Cy7)
TLR1 适用: 人, 小鼠, 大鼠, Cow, 犬 WB, FACS 宿主: 兔 Polyclonal PE-Cy7

anti-Toll-Like Receptor 1 (TLR1) (AA 20-270) antibody
TLR1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Toll-Like Receptor 1 (TLR1) (AA 321-420) antibody
TLR1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Toll-Like Receptor 1 (TLR1) (AA 605-785) antibody
TLR1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
状态

Liquid

浓度

0.25 mg/mL

缓冲液

PBS with 0.09 % (W/V) Sodium Azide as preservative.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
抗原

TLR1 (Toll-Like Receptor 1 (TLR1))

别名

CD281 / TLR1 (TLR1 产品)

别名

CD281 antibody, TIL antibody, TIL. LPRS5 antibody, rsc786 antibody, toll like receptor 1 antibody, toll-like receptor 1 antibody, TLR1 antibody, Tlr1 antibody

背景

Higher animals establish host defense by orchestrating innate and adaptive immunity. This is mediated by professional antigen presenting cells, i.e. dendritic cells (DCs). DCs can incorporate pathogens, produce a variety of cytokines, maturate, and present pathogen-derived peptides to T cells, thereby inducing T cell activation and differentiation. These responses are triggered by microbial recognition through type I transmembrane proteins, Toll-like receptors (TLRs) on DCs. TLRs consist of ten members and each TLR is involved in recognizing a variety of microorganism-derived molecular structures. TLR ligands include cell wall components, proteins, nucleic acids, and synthetic chemical compounds, all of which can activate DCs as immune adjuvants. Each TLR can activate DCs in a similar, but distinct manner. For example, TLRs can be divided into subgroups according to their type I interferon (IFN) inducing ability. TLR2 cannot induce IFN-alpha or IFN-beta, but TLR4 can lead to IFN-beta production. Meanwhile, TLR3, TLR7, and TLR9 can induce both IFN-alpha and IFN-beta. Recent evidences suggest that cytoplamic adapters for TLRs are especially crucial for this functional heterogeneity.Synonyms: KIAA0012, TIL, Toll-like receptor 1, Toll/interleukin-1 receptor-like protein

基因ID

21897, 10090

UniProt

Q9EPQ1

途径

TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades