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LIN28B 抗体 (Center)

LIN28B 适用: 人 WB, FACS, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN357013
发货至: 中国
  • 抗原 See all LIN28B 抗体
    LIN28B (Lin-28 Homolog B (LIN28B))
    抗原表位
    • 11
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 52
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 51
    • 1
    • 1
    克隆类型
    • 51
    • 2
    多克隆
    标记
    • 32
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LIN28B antibody is un-conjugated
    应用范围
    • 38
    • 25
    • 24
    • 23
    • 20
    • 5
    • 5
    • 3
    • 3
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects LIN28B at center.
    交叉反应 (详细)
    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.
    纯化方法
    Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    KLH conjugated synthetic peptide selected from the Center region of human LIN28B
    亚型
    Ig Fraction
    Top Product
    Discover our top product LIN28B Primary Antibody
  • 应用备注
    ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS, 0.09 % (W/V) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    LIN28B (Lin-28 Homolog B (LIN28B))
    别名
    LIN28B (LIN28B 产品)
    别名
    csdd2 antibody, LIN-28 antibody, CSDD2 antibody, 2810403D23Rik antibody, D030047M17Rik antibody, Lin-28.2 antibody, lin-28 homolog B antibody, lin-28 homolog B S homeolog antibody, lin-28 homolog B (C. elegans) antibody, LIN28B antibody, lin28b antibody, lin28b.S antibody, Lin28b antibody
    背景
    Lin-28 homolog B (LIN28B) is overexpressed in hepatocellular carcinoma. The heterochronic gene lin-28 is a key regulator of developmental timing in the nematode Caenorhabditis elegans. Similar with lin-28 proteins, LIN28B conserves a cold shock domain and a pair of CCHC zinc finger domains. Phylogenetic analysis suggests that they might arise as a result of duplication from an ancestral gene. Overexpression of LIN28B was noted in most HCC cell lines and clinical samples. A short LIN28B isoform was also identified in non-tumor liver tissue and fetal liver. Although predominantly localized in the cytoplasm, LIN28B protein shows cell cycle-dependent nuclear translocation in Huh7 cells. Induced expression of exogenous LIN28B in a tet-off cell line promoted cancer cell proliferation.Synonyms: CSDD2, LIN28B, Lin-28 homolog B
    分子量
    26953 Da
    基因ID
    389421, 9606
    UniProt
    Q6ZN17
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