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PUMA 抗体 (BH3 Domain, C-Term)

BBC3 适用: 人, 小鼠 WB, FACS, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN356830
发货至: 中国
  • 抗原 See all PUMA (BBC3) 抗体
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    抗原表位
    • 16
    • 12
    • 9
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    BH3 Domain, C-Term
    适用
    • 91
    • 40
    • 37
    • 16
    人, 小鼠
    宿主
    • 88
    • 6
    • 1
    克隆类型
    • 80
    • 15
    多克隆
    标记
    • 47
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PUMA antibody is un-conjugated
    应用范围
    • 76
    • 34
    • 29
    • 20
    • 15
    • 14
    • 13
    • 11
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    特异性
    This antibody is specific to Human and Mouse PUMA (BH3 Domain). Other species not tested.
    纯化方法
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    免疫原
    Synthetic peptide selected from the C-terminal region of Human PUMA
    亚型
    Ig Fraction
    Top Product
    Discover our top product BBC3 Primary Antibody
  • 应用备注
    ELISA: 1/1,000. Western blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    别名
    PUMA (BBC3 产品)
    别名
    BBC3 antibody, Puma antibody, JFY-1 antibody, JFY1 antibody, PUMA antibody, PUMA/JFY1 antibody, BCL2 binding component 3 antibody, Bcl-2 binding component 3 antibody, BBC3 antibody, Bbc3 antibody, bbc3 antibody
    背景
    PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.Synonyms: BBC3, Bcl-2-binding component 3, JFY-1, p53 up-regulated modulator of apoptosis
    分子量
    20532 Da
    基因ID
    27113, 9606
    UniProt
    Q9BXH1
    途径
    p53 Pathway, Positive Regulation of Endopeptidase Activity
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