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- 抗原 See all MBD2 抗体
- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
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抗原表位
- N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MBD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody is specific to MBD2 (N-term).
- 纯化方法
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- 免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MBD2.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product MBD2 Primary Antibody
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anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (Internal Region) antibody
Verified MBD2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 250-279) antibodyMBD2 适用: 人 WB, IF 宿主: 兔 Polyclonal RB41663 unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (N-Term) antibodyMBD2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 145-411) antibodyMBD2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 10-228) antibodyMBD2 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 1812CT625-9-45 unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 202-411) antibodyMBD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) antibodyMBD2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (Middle Region) antibodyMBD2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (N-Term) antibodyMBD2 适用: 人, 小鼠, 大鼠, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (Internal Region) antibodyMBD2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA: 1/1,000. Western blot: 1/100approx. 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.25 mg/mL
- 缓冲液
- PBS containing 0.09 % (W/V) Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- 抗原
- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
- 别名
- MBD2 (MBD2 产品)
- 背景
- DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing.Synonyms: DMTase, Demethylase, Methyl-CpG-binding domain protein 2
- 基因ID
- 8932
- NCBI登录号
- NP_003918
- UniProt
- Q9UBB5
- 途径
- Chromatin Binding
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