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JMJD4 抗体 (C-Term)

JMJD4 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN356562
发货至: 中国
  • 抗原 See all JMJD4 products
    JMJD4 (Jumonji Domain Containing 4 (JMJD4))
    抗原表位
    • 8
    • 8
    • 5
    • 4
    • 1
    • 1
    • 1
    C-Term
    适用
    • 26
    • 11
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 26
    克隆类型
    • 26
    多克隆
    标记
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    This JMJD4 antibody is un-conjugated
    应用范围
    • 26
    • 15
    • 8
    • 4
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody will recognize JMJD4 (C-term). It Cross reacts with Mouse (Predicted by 100 % Antigen Homology).
    纯化方法
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    免疫原
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human JMJD4.
    亚型
    Ig Fraction
  • 应用备注
    ELISA: 1/1,000. Western Blot: 1/250-1/500. Immunohistochemistry: 1/10approx. 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS containing 0.09 % (W/V) Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    JMJD4 (Jumonji Domain Containing 4 (JMJD4))
    别名
    JMJD4 (JMJD4 产品)
    别名
    JMJD4 antibody, 6430559I23 antibody, RGD1307186 antibody, jumonji domain containing 4 antibody, jumonji domain containing 4 L homeolog antibody, JMJD4 antibody, jmjd4.L antibody, Jmjd4 antibody
    背景
    Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.Synonyms: JmjC domain-containing protein 4, Jumonji domain-containing protein 4
    基因ID
    65094, 9606
    UniProt
    Q9H9V9
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