电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Ubiquitin 抗体

Ubiquitin 适用: 人, 小鼠, 大鼠, Cow, 马 IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN356468
发货至: 中国
  • 抗原 See all Ubiquitin 抗体
    Ubiquitin
    适用
    • 141
    • 70
    • 69
    • 66
    • 17
    • 17
    • 15
    • 14
    • 13
    • 13
    • 13
    • 13
    • 12
    • 11
    • 10
    • 9
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 马
    宿主
    • 100
    • 73
    • 3
    • 1
    • 1
    • 1
    克隆类型
    • 94
    • 85
    多克隆
    标记
    • 77
    • 13
    • 12
    • 10
    • 10
    • 9
    • 7
    • 7
    • 7
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Ubiquitin antibody is un-conjugated
    应用范围
    • 162
    • 90
    • 82
    • 60
    • 57
    • 42
    • 27
    • 21
    • 20
    • 14
    • 13
    • 9
    • 4
    • 1
    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody stains senile plaques and neurons.
    Cellular Localization: Nuclear, Cytoplasmic, and cell membrane.
    纯化方法
    Protein A Chromatography
    免疫原
    Purified Human Ubiquitin.
    亚型
    IgG
    Top Product
    Discover our top product Ubiquitin Primary Antibody
  • 应用备注
    Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears): 1/50-1/100 usingstreptavidinapprox. biotin system or polymer system. FFPE tissue sections require antigenretriever, boiling tissue for 15-20 minutes in 10 mM citrate, pH 6.0, followed by cooling atRT for 15-20 minutes. Immunofluorescence. Recommended Positive Control: Human brain from Alzheimer's disease.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    3 mg/mL
    缓冲液
    PBS, pH 7.4 containing 1 % BSA as stabilizer and 0.05 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • 抗原
    Ubiquitin
    别名
    Ubiquitin (Ubiquitin 产品)
    背景
    Ubiquitin is a 76 amino acids 8.5 kDa, a highly conserved small regulatory protein that is ubiquitously expressed in eukaryotes and plays a central role in protein degradation. The Ubiquitin/proteosome pathways are main, non-lysomal route for intracellular protein degradation. The protein to be degraded is conjugated to Ubiquitin, it is selectively degraded by 26S complex multicatalytic cytosolic and nuclear protease termed proteosome. This protein also plays important role in cellular processes e.g. Cell cycle progression, gene transcription, antigen processing and signal transduction. In Immunohistochemistry (IHC) this antibody can detect abnormal inclusion bodies, in neurofibrillary tangles in Alzheimer's disease, lewy bodies in Parkinson's disease, pick bodies in Pick's disease, inclusions in motor neuron disease, Mallory's Haylin in alcoholic liver disease and Rosenthal fibers in astrocytes.Synonyms: Polyubiquitin-B, UBB
    基因ID
    7314
    UniProt
    P0CG47
    途径
    Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway
You are here:
客服