A synthetic peptide from the internal region of human Rho related GTP binding protein RhoU (CDC42 like GTPase 1, CDC42L1, Ryu GTPase) conjugated to an immunogenic carrier protein was used as the antigen. The antigen shares 90% identity with rat and mouse sequence.
RHOU
适用: 小鼠, 大鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 350
应用备注
IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
注意事项
Avoid freeze and thaw cycles.
储存条件
4 °C/-20 °C
储存方法
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
ARHU antibody, CDC42L1 antibody, DJ646B12.2 antibody, WRCH1 antibody, fJ646B12.2 antibody, hG28K antibody, 2310026M05Rik antibody, AI182090 antibody, Arhu antibody, G28K antibody, WRCH-1 antibody, mG28K antibody, arhu antibody, hg28k antibody, wrch1 antibody, wrch-1 antibody, cdc42l1 antibody, MGC107947 antibody, fj646b12.2 antibody, zgc:101642 antibody, wu:fb18g01 antibody, zgc:110357 antibody, Wrch antibody, rac-2 antibody, rhou antibody, xg28k antibody, ras homolog family member U antibody, ras homolog gene family, member U antibody, ras homolog family member Ua antibody, ras homolog family member Ub antibody, ras homolog family member U L homeolog antibody, RHOU antibody, Rhou antibody, rhou antibody, rhoua antibody, rhoub antibody, rhou.L antibody
背景
Function: Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound. Subcellular location: Cell membrane, Lipid-anchor, Cytoplasmic side. Golgi apparatus membrane, Lipid-anchor. Cell junction âÄ° focal adhesion. Cell projection âÄ° podosome. Note: Localizes to podosomes in SRC-transformed cells. Tissue specificity: Ubiquitously expressed in all tissues examined. Expressed at high levels in the stomach, small intestine, brain, skeletal muscle and placenta.,Rho Family,Rho related GTP binding protein RhoU, RhoU, Ryu GTPase, CDC42-like GTPase 1, Rho GTPase-like protein ARHU, GTP-binding protein-like 1, ARHU, CDC42L1, G28K, WRCH1, Wnt-1 responsive Cdc42 homolog 1