Pro BDNF (proBDNF)
(Pro-Brain-Derived Neurotrophic Factor (proBDNF))
适用
大鼠
宿主
绵羊
克隆类型
多克隆
标记
This Pro BDNF antibody is un-conjugated
应用范围
Immunohistochemistry (IHC), Western Blotting (WB)
特异性
Specific for proBDNF.
交叉反应
小鼠, 大鼠
交叉反应 (详细)
Other species not yet tested.
纯化方法
IgG
免疫原
A synthetic peptide from rat proBDNF conjugated to blue carrier protein was used as the antigen. The peptide is homologous in mouse and zebrafish and shares 96% identity with human sequence.
IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
注意事项
Avoid freeze and thaw cycles.
储存条件
4 °C/-20 °C
储存方法
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
有效期
12 months
抗原
Pro BDNF (proBDNF)
(Pro-Brain-Derived Neurotrophic Factor (proBDNF))
FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted.,BDNF,Brain-derived neurotrophic factor precursor, proBDNF, pro BDNF