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Rho-related GTP-binding protein 抗体

RhO (pan) 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 绵羊 Polyclonal unconjugated
产品编号 ABIN350723
发货至: 中国
  • 抗原 See all Rho-related GTP-binding protein (RhO (pan)) 抗体
    Rho-related GTP-binding protein (RhO (pan))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 23
    • 4
    绵羊
    克隆类型
    • 22
    • 5
    多克隆
    标记
    • 18
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    This Rho-related GTP-binding protein antibody is un-conjugated
    应用范围
    • 20
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    Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    Specific for RhO family.
    免疫原
    A synthetic peptide as a part of human/rat/mouse/chicken/dog/frog (and more species) Rho-related GTP-binding proteins (RhOA, RhOB, RhOC, RhOF, RhOQ) and RAC1, RAC2, RAC3 and CDC42 conjugated to an immunogenic carrier protein was used as the immunogen.
    亚型
    IgG
    Top Product
    Discover our top product RhO (pan) Primary Antibody
  • 应用备注
    A concentration of 10-50 µg/ml is recommended.
    The optimal concentration should be determined by the end user.
    Not yet tested in other applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
    注意事项
    Avoid freeze and thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    有效期
    12 months
  • 抗原
    Rho-related GTP-binding protein (RhO (pan))
    Abstract
    RhO (pan) 产品
    物质类
    Chemical
    背景
    The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Also known as: Rho-related GTP-binding protein RhOA, RhOB, RhOC, RhOF, RhOQ, RAC1, RAC2, RAC3, CDC42.
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