Highly specific for mature olfactory neurons (including axon and terminals).
交叉反应
小鼠, 大鼠
交叉反应 (详细)
Other species have not yet been tested.
纯化方法
IgG
免疫原
A synthetic peptide from rat Olfactory Marker Protein conjugated to blue carrier protein has been used as the antigen. The peptide is homologous in mouse.
IHC, WB. Use at a concentration of 5-10 μg,ml. The optimal dilution should be determined by the end user. For IHC, Zamboni's,4 % PFA fixatives are recommended.
限制
仅限研究用
状态
Lyophilized
溶解方式
Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
注意事项
Avoid freeze and thaw cycles.
储存条件
4 °C/-20 °C
储存方法
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
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背景
Olfactory marker protein (OMP) is an abundant, 19- kDa, cytosolic protein that is almost exclusively expressed in mature, functioning, olfactory neurons but not in the neural precursor basal cells. The OMP gene structure and protein sequence are highly conserved between mouse, rat and human. Its tissue-specific expression in the receptor cells together with the results of the mouse knockout studies show that OMP represents a novel modulatory component of the odor detection/signal transduction cascade. FUNCTION: May act as a modulator of the olfactory signal-transduction cascade. SUBUNIT: Interacts with BEX1 and BEX2. SUBCELLULAR LOCATION: Cytoplasm. TISSUE SPECIFICITY: Uniquely associated with mature olfactory receptor neurons. SIMILARITY: Belongs to the olfactory marker protein family.<||a href="http://senselab.med.yale.edu/senselab/ordb/" ><||/a><||a href="http://www.enzim.hu/hmmtop1.1/server/submit.html" > <||/a>,OMP,Olfactory neuronal-specific protein