MAP1LC3A
(Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
适用
人
宿主
绵羊
克隆类型
多克隆
标记
This MAP1LC3A antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (IHC)
特异性
Specific for MAP1LC3A.
交叉反应
人, 小鼠, 大鼠
交叉反应 (详细)
Other species not yet tested.
纯化方法
IgG
免疫原
A synthetic peptide from human microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A, MAP1A/MAP1B LC3 A) conjugated to an immunogenic carrier protein has been used as the antigen. The peptide is homologous in rat and mouse.
IHC, WB. Use at a concentration of 10-50 μg,ml. The optimal workiing concentration should be determined by the end user. Not yet tested in other applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
注意事项
Avoid freeze and thaw cycles.
储存条件
4 °C/-20 °C
储存方法
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
有效期
12 months
抗原
MAP1LC3A
(Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. This protein is probably involved in formation of autophagosomal vacuoles. SUBCELLULAR LOCATION: Cytoplasm. Intracytoplasmic membrane, Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane, Lipid-anchor. Note: LC3-II binds to the autophagic membranes. TISSUE SPECIFICITY: Most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes.,Mammalian Autophagy,MAP1A/MAP1B LC3 A, MAP1A/1B light chain 3 A, MAP1 light chain 3-like protein 1, Microtubule-associated protein 1 light chain 3 alpha, Autophagy-related protein LC3 A Autophagy-related ubiquitin-like modifier LC3 A, MAP1ALC3, MAP1BLC3, MAP1LC3A