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LGR4 抗体 (Internal Region)

LGR4 适用: 人, Chimpanzee, Macaque ELISA, WB, IHC 宿主: 小鼠 Monoclonal 6G8-B3-G5-C3 unconjugated
产品编号 ABIN349637
发货至: 中国
  • 抗原 See all LGR4 抗体
    LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))
    抗原表位
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 33
    • 12
    • 10
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人, Chimpanzee, Macaque
    宿主
    • 25
    • 4
    • 4
    小鼠
    克隆类型
    • 25
    • 8
    单克隆
    标记
    • 22
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LGR4 antibody is un-conjugated
    应用范围
    • 11
    • 10
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    特异性
    This product was purified from concentrated tissue culture supernate by Protein A chromatography. This antibody is specific for human LGR4 protein. A BLAST analysis was used to suggest cross-reactivity with LGR4 from chimpanzee, orangutan and macaque based on 100% homology with the immunizing sequence. Cross-reactivity with LGR4 from other sources has not been determined.
    交叉反应
    Chimpanzee, Macaque
    产品特性
    LGR4, also known as leucine-rich repeat-containing G protein-coupled receptor 4, is a G protein-coupled receptors (GPCRs). GPCRs are membrane bound proteins that play key roles in a variety of physiologic functions. Members of the leucine-rich GPCR (LGR) family, such as GPR48, have multiple N-terminal leucine-rich repeats (LRRs) and a 7-transmembrane domain. LGR4 is an orphan GPCR reported to be expressed in steroidogenic tissues such as placenta, ovary, testis, adrenal, pancreas, prostate, and thyroid, as well as in spinal cord, stomach, heart, and kidney.
    纯化方法
    purified
    过滤
    Sterile filtered
    免疫原
    This monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human LGR4 protein. The hybridoma was produced by fusing BALB/c mouse splenocytes and mouse myeloma SP2/O cells using conventional technology.
    Immunogen Type: Peptide
    克隆位点
    6G8-B3-G5-C3
    亚型
    IgG2b kappa
    Top Product
    Discover our top product LGR4 Primary Antibody
  • 应用备注
    This monoclonal antibody is suitable for ELISA, immunohistochemistry and western blotting. Expect a band approximately 102 kDa in size corresponding to LGR4 protein by western blotting in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user. Use formalin-fixed paraffin-embedded sections for immunohistochemistry. No pre-treatment of sample is required.
    说明

    Gene Name: LGR4

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.13 mg/mL
    缓冲液
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is three (3) months from date of opening.
    有效期
    3 months
  • Yi, Xiong, Gong, Bellister, Ellis, Liu: "Analysis of LGR4 receptor distribution in human and mouse tissues." in: PLoS ONE, Vol. 8, Issue 10, pp. e78144, (2014) (PubMed).

  • 抗原
    LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))
    别名
    LGR4 (LGR4 产品)
    别名
    BNMD17 antibody, GPR48 antibody, 9130225G07 antibody, A330106J01Rik antibody, A930009A08Rik antibody, Gpr48 antibody, leucine rich repeat containing G protein-coupled receptor 4 antibody, leucine-rich repeat-containing G protein-coupled receptor 4 antibody, LGR4 antibody, Lgr4 antibody
    背景
    LGR4, also known as leucine-rich repeat-containing G protein-coupled receptor 4, is a G protein-coupled receptors (GPCRs). GPCRs are membrane bound proteins that play key roles in a variety of physiologic functions. Members of the leucine-rich GPCR (LGR) family, such as GPR48, have multiple N-terminal leucine-rich repeats (LRRs) and a 7-transmembrane domain. LGR4 is an orphan GPCR reported to be expressed in steroidogenic tissues such as placenta, ovary, testis, adrenal, pancreas, prostate, and thyroid, as well as in spinal cord, stomach, heart, and kidney.
    Synonyms: LGR4 leucine-rich repeat-containing G protein-coupled receptor 4
    基因ID
    55366, 157694513
    UniProt
    Q8N537
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