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SERPINB2 抗体 (Internal Region)

Name: SERPINB2 抗体 (Internal Region)
SKU: ABIN349627
Availability: OutOfStock

Rockland 600-401-b22 SERPINB2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

Western blot using affinity purified anti-PAI-2 antibody shows detection of endogenous PAI-2 in 50 µg of HeLa whole cell lysates. (SERPINB2 抗体 (Internal Region))

Immunohistochemistry of rabbit anti-Plasminogen Activator 2 antibody (ABIN349627). (SERPINB2 抗体 (Internal Region))

IHC (p)

2 images

(1 reference)

产品编号 ABIN349627

Supplier Product No.: 600-401-b22

发货至: 中国

Datasheet as PDF

抗原 See all SERPINB2 抗体

SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))
抗原表位
15

6

4

3

2

2

2

1

1

1

1

1

1

1

1

1
Internal Region
适用
47

12

9

3

3

2

2

2

2

1
人
宿主
46

8

1

1
兔
Compatible Secondaries
克隆类型
50

5
多克隆
标记
29

4

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This SERPINB2 antibody is un-conjugated
应用范围
29

17

13

13

12

7

7

6

4

3

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Supplier Product No.

600-401-b22

Supplier

Rockland

原理

Plasminogen Activator Inhibitor 2 Antibody

交叉反应（详细）

This affinity-purified antibody is directed against human PAI-2 protein.

产品特性

Synonyms: rabbit anti-PAI-2 antibody, rabbit anti-plasminogen activator inhibitor 2 antibody, Placental plasminogen activator inhibitor, Monocyte Arg-serpin, Urokinase inhibitor, SERPINB2, Serpin B2, serpin peptidase inhibitor, PAI2, PLANH2

纯化方法

The product was affinity purified from monospecific antiserum by immunoaffinity purification.

过滤

Sterile filtered

免疫原

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to an internal area of human PAI-2 protein.
Immunogen Type: Conjugated Peptide

亚型

IgG

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anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 154-408) antibody
SERPINB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A4 unconjugated

anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-100) antibody
SERPINB2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3A9 unconjugated

anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 154-408) antibody
SERPINB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 293-389) antibody
SERPINB2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 1-415) antibody
SERPINB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (Internal Region) antibody
SERPINB2 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 170-393) antibody
SERPINB2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

anti-Plasminogen Activator Inhibitor 2 (SERPINB2) (AA 116-144) antibody
SERPINB2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB19097 unconjugated

应用备注

Immunohistochemistry Dilution: 10 μg/mL
Application Note: This affinity purified antibody has been tested for use in ELISA, Immunochemistry, and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band 42-46.6 kDa in size corresponding to PAI-2 protein by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:500 - 1:2,000
ELISA Dilution: 1:100,000 - 150,000
Other: User Optimized

限制

仅限研究用
状态

Liquid

浓度

1.2 mg/mL

缓冲液

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

有效期

12 months
Godtfredsen, Sidelmann, Dolleris, Jørgensen, Johansen, Pedersen, Palarasah, Gram: "Fibrinolytic Changes in Women with Preeclampsia." in: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, Vol. 28, pp. 10760296221126172, (2022) (PubMed).
抗原

SERPINB2 (Plasminogen Activator Inhibitor 2 (SERPINB2))

别名

SERPINB2 (SERPINB2 产品)

物质类

Amino Acid

背景

Background: Extracellular plasminogen activator inhibitor type-2 (also known as PAI-2, Placental plasminogen activator inhibitor, Monocyte Arg-serpin, Urokinase inhibitor, SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2) is a coagulation factor and a potent inhibitor of urokinase-type plasminogen activator (u-PA) and also acts as a multifunctional protein. It is present in most cells, especially monocytes and macrophages. PAI-2 exists in two forms, a 60- kDa, secreted, extracellular, glycosylated form and a 43- kDa intracellular form. It is a multifunctional protein that plays a role in cell differentiation, in prevention of programmed cell death, in the regulation of cell proliferation, in the inhibition of microbial proteinases and in the protection against stromal degradation. High levels of the PAI-2 protein are associated with a good prognosis in breast cancer, small cell lung, ovarian cancer, and inhibition of metastasis. PAI-2 also plays a role in inflammation on the surface of the eye. PAI-2 may cooperate with pRb2/p130 in modulating PAI-2 gene expression by chromatin remodeling.

基因ID

5055, 4505595

UniProt

P05120

途径

Autophagy