TRIM29 抗体 (acLys116)
(2 references)-
- 抗原 See all TRIM29 抗体
- TRIM29 (Tripartite Motif Containing 29 (TRIM29))
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抗原表位
- acLys116
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适用
- 人, Cow, 马, Macaque, Chimpanzee
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRIM29 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- ATDC Ac-K116 Antibody
- 交叉反应 （详细）
- This antibody reacts with over-expressed, acetylated lysine ATDC protein.
- 产品特性
- Synonyms: rabbit anti-ATDC Ac-K116 Antibody, rabbit anti-ATDC acetylated Lys116 Antibody, Ataxia-telangiectasia group D associated protein antibody, FLJ36085 antibody, TRIM 29 antibody, Tripartite motif containing protein 29 antibody, TRIM-29
- 纯化方法
- This product was affinity purified from monospecific antiserum by immunoaffinity chromatography.
- 过滤
- Sterile filtered
- 免疫原
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Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to an internal portion of human ATDC protein around lysine 116.
Immunogen Type: Conjugated Peptide
- 亚型
- IgG
- Top Product
- Discover our top product TRIM29 Primary Antibody
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anti-Tripartite Motif Containing 29 (TRIM29) (AA 451-588) antibody
TRIM29 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8C8G5 unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (Internal Region) antibodyVerified TRIM29 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 1-200) antibodyTRIM29 适用: 人 ELISA, IHC, Coat, StM 宿主: 小鼠 Monoclonal TRIM29-1041 unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (Internal Region) antibodyTRIM29 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 1-200) antibodyTRIM29 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-629M unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 309-588) antibodyTRIM29 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 1-588) antibodyTRIM29 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 1-200) antibodyTRIM29 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal TRIM29-1042 unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (C-Term) antibodyTRIM29 适用: 人, 小鼠, 大鼠, Cow, 马, 豚鼠, 犬, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 29 (TRIM29) (AA 253-283) antibodyTRIM29 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Application Note: This affinity purified antibody has been tested for use in ELISA and western blotting. Specific conditions for reactivity and detection of ATDC Ac-K116 should be optimized by the end user. Expect a band approximately ~66 kDa in size corresponding to ATDC Ac-K116 by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:500 to 3,000
ELISA Dilution: 1:100,000
Other: User Optimized
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.67 mg/mL
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
- 有效期
- 12 months
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: "Histone deacetylase 9 (HDAC9) regulates the functions of the ATDC (TRIM29) protein." in: The Journal of biological chemistry, Vol. 285, Issue 50, pp. 39329-38, (2011) (PubMed).
: "The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions." in: Molecular and cellular biology, Vol. 30, Issue 12, pp. 3004-15, (2010) (PubMed).
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: "Histone deacetylase 9 (HDAC9) regulates the functions of the ATDC (TRIM29) protein." in: The Journal of biological chemistry, Vol. 285, Issue 50, pp. 39329-38, (2011) (PubMed).
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- 抗原
- TRIM29 (Tripartite Motif Containing 29 (TRIM29))
- 别名
- TRIM29 (TRIM29 产品)
- 背景
- Background: Ataxia-telangiectasia group D-associated protein (ATDC), also called tripartite motif-containing protein 29 (TRIM29), is a novel Histone deacetylase (HDAC) associated protein. Its function is tightly regulated by HDAC. ATDC Lysine 116 (K116) is acetylated and has a significant functional role in regulating cell survival and tumorigenesis. ATDC is expressed in placenta, prostate and thymus, and is over expressed in pancreatic and cervical tumors. Its function in tumor cells is not fully understood. It is constitutively phosphorylated by PKC on serine/threonine in A431 cells. The ATDC gene product is one of a group of proteins that share multiple zinc finger motifs and an adjacent leucine zipper motif. These proteins have been proposed to form homo- or heterodimers involved in nucleic acid binding, consistent with the fact that many of these proteins appear to be transcriptional regulatory factors involved in carcinogenesis and/or differentiation. The likelihood that the ATDC gene product is involved in transcriptional regulation could explain the pleiomorphic characteristics of AT, including abnormal cell cycle regulation.
- 基因ID
- 23650, 17402909
- UniProt
- Q14134
- 途径
- p53 Pathway, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus
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