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- 抗原 See all PTENP1 products
- PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTENP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- This affinity-purified antibody is directed against human PTEN-P1 protein. The product was affinity purified from monospecific antiserum by immunoaffinity purification. Reactivity occurs against human PTEN-P1 protein. A BLAST analysis was used to suggest cross reactivity with PTEN proteins from mouse,
- 产品特性
- This gene (PTENP1) is a highly homologous pseudogene of PTEN. PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.
- 纯化方法
- affinity purified
- 过滤
- Sterile filtered
- 免疫原
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This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a peptide corresponding to amino acids near the N-terminal end of human PTEN-P1 protein.
Immunogen Type: Peptide - 亚型
- IgG
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anti-Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1) (AA 1-369) antibody
PTENP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1) (N-Term) antibodyPTENP1 适用: 人, 小鼠, 大鼠, 斑马鱼, Chimpanzee, 犬, Green Pufferfish, Macaque WB, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- This affinity purified antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 55 kDa in size corresponding to PTEN-P1 protein by western blotting in the appropriate cell lysate or extract.
- 说明
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Gene Name: PTENP1
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.15 mg/mL
- 缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is three (3) months from date of opening.
- 有效期
- 3 months
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- 抗原
- PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))
- 别名
- PTEN-P1 (PTENP1 产品)
- 别名
- PTEN-rs antibody, PTEN2 antibody, PTENpg1 antibody, PTH2 antibody, psiPTEN antibody, phosphatase and tensin homolog pseudogene 1 antibody, PTENP1 antibody
- 背景
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This gene (PTENP1) is a highly homologous pseudogene of PTEN. PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.
Synonyms: Phosphatase and tensin homolog pseudogene 1 antibody, psiPTEN antibody, PTEN rs antibody, PTEN2 antibody, PTH2 antibody, TEP1 antibody - 基因ID
- 5728, 73765544
- UniProt
- O43460
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