TTC3 抗体 (N-Term)
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- 抗原 See all TTC3 抗体
- TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TTC3 antibody is un-conjugated
- 应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF)
- 特异性
- Reacts with human E3 ubiquitin-protein ligase TTC3
- 纯化方法
- Antiserum
- 免疫原
- Synthetic peptide derived from Cter domain of human TTC3
- 亚型
- IgG
- Top Product
- Discover our top product TTC3 Primary Antibody
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- 应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IF(1:100 - 1:500) WB(1:500 - 1:5000) - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Must be reconstituted in distilled water.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- 有效期
- 24 months
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- 抗原
- TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
- 别名
- E3 ubiquitin-protein ligase TTC3 (TTC3 产品)
- 别名
- DCRR1 antibody, RNF105 antibody, TPRDIII antibody, 2610202A04Rik antibody, AA409221 antibody, D16Ium21 antibody, D16Ium21e antibody, TPRD antibody, mKIAA4119 antibody, TTC3 antibody, tetratricopeptide repeat domain 3 antibody, E3 ubiquitin-protein ligase TTC3 antibody, TTC3 antibody, Ttc3 antibody, LOC100562480 antibody
- 背景
- E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.
- UniProt
- P53804
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