AMBRA1 抗体 (N-Term)
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- 抗原 See all AMBRA1 抗体
- AMBRA1 (Autophagy/beclin-1 Regulator 1 (AMBRA1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AMBRA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
- 特异性
- Reacts with mouse 120 kDa Ambra1 protein
- 交叉反应
- 大鼠
- 交叉反应 (详细)
- Cross reacts with human and rat protein.
- 纯化方法
- Antiserum
- 免疫原
- Synthetic peptide derived from N-term domain of the mouse Ambra 1 protein.
- 亚型
- IgG
- Top Product
- Discover our top product AMBRA1 Primary Antibody
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- 应用备注
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Working dilution: Optimal dilution should be determined by the end user.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Must be reconstituted in distilled water.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- 有效期
- 24 months
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Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, (2011) (PubMed).
: "The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy." in: The Journal of cell biology, Vol. 191, Issue 1, pp. 155-68, (2010) (PubMed).
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Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, (2011) (PubMed).
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- 抗原
- AMBRA1 (Autophagy/beclin-1 Regulator 1 (AMBRA1))
- 别名
- Activating Molecule in BECN1-Regulated Autophagy Protein 1 (Ambra1) (AMBRA1 产品)
- 别名
- 2310079H06Rik antibody, A130023A14 antibody, AA474864 antibody, AV021921 antibody, D030051N19Rik antibody, mKIAA1736 antibody, Nyw1 antibody, DCAF3 antibody, WDR94 antibody, autophagy and beclin 1 regulator 1 antibody, autophagy/beclin-1 regulator 1a antibody, autophagy/beclin 1 regulator 1 antibody, AMBRA1 antibody, ambra1a antibody, Ambra1 antibody
- 背景
- Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation
- 基因ID
- 55626
- UniProt
- Q9C0C7
- 途径
- Autophagy
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