DPYSL3 抗体 (C-Term)
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- 抗原 See all DPYSL3 抗体
- DPYSL3 (Dihydropyrimidinase-Like 3 (DPYSL3))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DPYSL3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 特异性
- Reacts with 65 kDa CRMP-4 from human rat and mouse
- 交叉反应 (详细)
- Do not react with CRMP-1, CRMP-2, CRMP-3 or CRMP-5.
- 纯化方法
- Antiserum
- 免疫原
- A 15 residue synthetic peptide derived from C-terminal domain of human collapsing-response mediator
- 亚型
- IgG
- Top Product
- Discover our top product DPYSL3 Primary Antibody
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- 应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
-IHC : 1/500 - WB :1/2 000 - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Must be reconstituted in distilled water.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- 有效期
- 24 months
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A rare motor neuron deleterious missense mutation in the DPYSL3 (CRMP4) gene is associated with ALS." in: Human mutation, Vol. 34, Issue 7, pp. 953-60, (2013) (PubMed).
: "Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain." in: The Journal of comparative neurology, Vol. 486, Issue 1, pp. 1-17, (2005) (PubMed).
: "Isolation and expression pattern of human Unc-33-like phosphoprotein 6/collapsin response mediator protein 5 (Ulip6/CRMP5): coexistence with Ulip2/CRMP2 in Sema3a- sensitive oligodendrocytes." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 21, Issue 18, pp. 7203-14, (2001) (PubMed).
: "Ulip/CRMP proteins are recognized by autoantibodies in paraneoplastic neurological syndromes." in: The European journal of neuroscience, Vol. 11, Issue 12, pp. 4226-32, (2000) (PubMed).
: "Analysis of transglutaminase-catalyzed isopeptide bonds in paired helical filaments and neurofibrillary tangles from Alzheimer's disease." in: Methods in enzymology, Vol. 309, pp. 172-86, (1999) (PubMed).
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A rare motor neuron deleterious missense mutation in the DPYSL3 (CRMP4) gene is associated with ALS." in: Human mutation, Vol. 34, Issue 7, pp. 953-60, (2013) (PubMed).
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- 抗原
- DPYSL3 (Dihydropyrimidinase-Like 3 (DPYSL3))
- 别名
- Collapsin Response Mediator Protein 4 (CRMP-4) (DPYSL3 产品)
- 别名
- CRMP4A antibody, CRMP4B antibody, dpysl3 antibody, DRP-3 antibody, MGC69487 antibody, dpysl3-b antibody, crmp4 antibody, CRMP-4 antibody, xCRMP4 antibody, DRP-3-B antibody, DPYSL3 antibody, CRMP4 antibody, DRP3 antibody, LCRMP antibody, ULIP antibody, ULIP-1 antibody, TUC4 antibody, Ulip antibody, Ulip1 antibody, Crmp4 antibody, TUC-4b antibody, drp-3 antibody, drp3 antibody, lcrmp antibody, nsp1 antibody, tuc-4 antibody, tuc4 antibody, ulip antibody, ulip-1 antibody, dihydropyrimidinase like 3 antibody, dihydropyrimidinase like 3 L homeolog antibody, dihydropyrimidinase-like 3 antibody, dihydropyrimidinase like 3 S homeolog antibody, DPYSL3 antibody, dpysl3 antibody, dpysl3.L antibody, Dpysl3 antibody, dpysl3.S antibody
- 背景
- Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration
- UniProt
- Q14195
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