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CD81 抗体 (PE)

CD81 适用: 人, 兔, Cat FACS 宿主: 小鼠 Monoclonal M38 PE
产品编号 ABIN343728
发货至: 中国
  • 抗原 See all CD81 抗体
    CD81
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD81 antibody is conjugated to PE
    应用范围
    • 123
    • 79
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    Flow Cytometry (FACS)
    特异性
    The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.
    交叉反应 (详细)
    Human, Feline (Cat), Rabbit
    纯化方法
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    MOLT-4 (human T-ALL cell line)
    克隆位点
    M38
    亚型
    IgG1
    Top Product
    Discover our top product CD81 Primary Antibody
  • 应用备注
    Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    说明

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    限制
    仅限研究用
  • 溶解方式
    No reconstitution is necessary.
    缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze.
    Avoid prolonged exposure to light.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Escola, Kleijmeer, Stoorvogel, Griffith, Yoshie, Geuze: "Selective enrichment of tetraspan proteins on the internal vesicles of multivesicular endosomes and on exosomes secreted by human B-lymphocytes." in: The Journal of biological chemistry, Vol. 273, Issue 32, pp. 20121-7, (1998) (PubMed).

    Imai, Kakizaki, Nishimura, Yoshie: "Molecular analyses of the association of CD4 with two members of the transmembrane 4 superfamily, CD81 and CD82." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 3, pp. 1229-39, (1995) (PubMed).

    Imai, Yoshie et al.: "C33 antigen and M38 antigen recognized by monoclonal antibodies inhibitory to syncytium formation by human T cell leukemia virus type 1 are both members of the transmembrane 4 superfamily and ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 151, Issue 11, pp. 6470-81, (1994) (PubMed).

    Fukudome, Furuse, Imai, Nishimura, Takagi, Hinuma, Yoshie et al.: "Identification of membrane antigen C33 recognized by monoclonal antibodies inhibitory to human T-cell leukemia virus type 1 (HTLV-1)-induced syncytium formation: altered glycosylation of C33 antigen ..." in: Journal of virology, Vol. 66, Issue 3, pp. 1394-401, (1992) (PubMed).

  • 抗原
    CD81
    别名
    CD81 (CD81 产品)
    别名
    Tapa-1 antibody, Tapa1 antibody, Tspan28 antibody, CVID6 antibody, S5.7 antibody, TAPA1 antibody, TSPAN28 antibody, CD81 molecule antibody, CD81 molecule b antibody, CD81 antigen antibody, Cd81 molecule antibody, CD81 antibody, cd81b antibody, Cd81 antibody
    背景
    CD81 Molecule,CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.,S5.7, CVID6, TAPA1, TSPAN28
    基因ID
    975
    UniProt
    P60033
    途径
    Inositol Metabolic Process, Hepatitis C
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