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- 抗原 See all AGR2+AGR3 products
- AGR2+AGR3
- 适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This AGR2+AGR3 antibody is un-conjugated
- 应用范围
- Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- The antibody AGR3.4 recognizes the PLMII epitope of AGR3 (AG3) and AGR2 (AG2) proteins (19-20 kDa), secreted cytoplasmic proteins which can serve as markers of carcinogenesis.
- 交叉反应 （详细）
- Human, Other species Not tested
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 免疫原
- Purified human AGR3 protein
- 克隆位点
- AGR3-4
- 亚型
- IgG1
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- 应用备注
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Immunohistochemistry (paraffin sections): Recommended dilution: 5 μg/mL, Positive tissue: human colon.
Western blotting: Recommended dilution: 1 μg/mL, positive control: T47D breast cancer cell line, negative control: H1299 lung carcinoma cell line.
Immunocytochemistry: Recommended dilution: 1 μg/mL, positive control: T47D breast cancer cell line, negative control: H1299 lung carcinoma cell line. - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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- 抗原
- AGR2+AGR3
- Abstract
- AGR2+AGR3 产品
- 别名
- AG3 antibody, BCMP11 antibody, HAG3 antibody, PDIA18 antibody, hAG-3 antibody, E030025L21Rik antibody, Gm888 antibody, anterior gradient 3, protein disulphide isomerase family member antibody, anterior gradient 3 antibody, AGR3 antibody, Agr3 antibody
- 背景
- AGR2 (Anterior Gradient 2), also known as AG2 (hAG-2, HAG2 in human), or GOB-4, and AGR3 (Anterior Gradient 3), also known as AG3 (hAG-3, HAG3 in human), or BCMP11, are secreted cytoplasmic proteins which are involved in metastasis induction and p53 tumour supressor inhibition. They may serve as molecular markers and potential therapeutic targets for hormone-responsive breast tumours, AGR2 was reported also as a marker of other carcinomas. Xenopus homolog of these proteins is associated with anteroposterior fate determination during early development.,AG2, AG3, HAG2, HAG3
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