HSP90 alpha/beta 抗体 (N-Term)
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- 抗原 See all HSP90 alpha/beta products
- HSP90 alpha/beta (Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta))
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抗原表位
- N-Term
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适用
- 人, 小鼠, Cow
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HSP90 alpha/beta antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- The antibody MBH90AB recognizes the epitope EEEVE within N-terminal part of ubiquitously expressed Hsp90 alpha and Hsp90 beta intracellular proteins with calculated Mw of 84.7 kDa and 83.3 kDa, respectively, however, migrating as 90 kDa bands under reducing SDS-PAGE conditions.
- 交叉反应 （详细）
- Human, Mouse, Bovine, Other not determined
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 免疫原
- Peptide corresponding to the sequence EEVHHGEEEVEC within N-terminal part of human Hsp90.
- 克隆位点
- MBH90AB
- 亚型
- IgG1
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anti-Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta) (AA 291-304) antibody
HSP90 alpha/beta 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 小鼠 Monoclonal Hyb-K41220A unconjugated
anti-Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta) (AA 291-304) antibody (FITC)HSP90 alpha/beta 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 小鼠 Monoclonal Hyb-K41220A FITC
anti-Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta) (AA 291-304) antibody (Biotin)HSP90 alpha/beta 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 小鼠 Monoclonal Hyb-K41220A Biotin
anti-Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta) (AA 291-304) antibody (Atto 488)HSP90 alpha/beta 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 小鼠 Monoclonal Hyb-K41220A Atto 488
anti-Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta) (AA 291-304) antibody (Atto 594)HSP90 alpha/beta 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 小鼠 Monoclonal Hyb-K41220A Atto 594
anti-Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta) (AA 291-304) antibody (Atto 390)HSP90 alpha/beta 适用: 人 WB, ELISA, IHC, IF, ICC 宿主: 小鼠 Monoclonal Hyb-K41220A Atto 390
anti-Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta) antibodyHSP90 alpha/beta 适用: 人, 大鼠, Saccharomyces cerevisiae, Schizosaccharomyces pombe WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal Hyb-K41220A unconjugated
anti-Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta) antibody (APC)HSP90 alpha/beta 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: Llama Polyclonal APC
anti-Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta) antibody (HRP)HSP90 alpha/beta 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: Llama Polyclonal HRP
anti-Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta) antibody (Alkaline Phosphatase (AP))HSP90 alpha/beta 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: Llama Polyclonal Alkaline Phosphatase (AP)
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- 应用备注
- Western blotting: Recommended dilution: 1 μg/mL.
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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- 抗原
- HSP90 alpha/beta (Heat Shock Protein 90 alpha/beta (HSP90 alpha/beta))
- 别名
- Hsp90 alpha,beta (HSP90 alpha/beta 产品)
- 背景
- Hsp90 (heat shock protein 90) is one of the most abundant chaperones in the cytosol of eukaryotic cells. It interacts with various proteins, including protein kinases and transcription factors, and either facilitates their stabilization and activation or directs them for proteasomal degradation. Hsp90 thus affects multiple signaling pathways and biological processes and modulation of this single target offers the prospect of simultaneous intervence to various key points of oncogenic transformation. Hsp90 operates as a dimer in a conformational cycle driven by ATP binding and hydrolysis. There are two isoforms, alpha and beta, of vertebrate Hsp90. Whereas Hsp90 beta is expressed constitutively to a high level, Hsp90 alpha is stress-inducible and is overexpressed in many cancerous cells.,HSP90A, HSP90B, LAP-2, LAP2, EL52
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