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- 抗原 See all LBP 抗体
- LBP (Lipopolysaccharide Binding Protein (LBP))
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适用
- 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This LBP antibody is un-conjugated
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应用范围
- ELISA
- 特异性
- Mouse LBP. The antibody blocks LPS binding to membrane bound CD14.
- 交叉反应
- 人, 大鼠
- 纯化方法
- Protein G affinity column
- 免疫原
- native mouse LBP
- 克隆位点
- BiG33
- 亚型
- IgG1
- Top Product
- Discover our top product LBP Primary Antibody
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- 应用备注
- ELISA ,LBP inhibition studies, Western Blot. inhibits binding of LPS to membrane bound CD14, (Inhibits LPS-binding (0.5 ug/ml) to CD14+CHO cells (2 x 106/ml) up to 1:1000, total inhibition 1:5 Binding titre at mouse LBP- ELISA: 1:50.000 Cross reacting with rat LBP
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Reconstitute with bidistilled water
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, pH 7.17
- 储存液
- Without preservative
- 储存条件
- -20 °C,-80 °C
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Binding of bacterial peptidoglycan to CD14." in: The Journal of biological chemistry, Vol. 273, Issue 15, pp. 8680-90, (1998) (PubMed).
: "Specific binding of soluble peptidoglycan and muramyldipeptide to CD14 on human monocytes." in: Infection and immunity, Vol. 65, Issue 3, pp. 858-64, (1997) (PubMed).
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Binding of bacterial peptidoglycan to CD14." in: The Journal of biological chemistry, Vol. 273, Issue 15, pp. 8680-90, (1998) (PubMed).
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- 抗原
- LBP (Lipopolysaccharide Binding Protein (LBP))
- 别名
- Lipopolysaccharide (LPS)-Binding Protein (LBP) (LBP 产品)
- 别名
- BPIFD2 antibody, Bpifd2 antibody, Ly88 antibody, LPSBP antibody, LBP antibody, lipopolysaccharide binding protein antibody, lipopolysaccharide-binding protein antibody, LBP antibody, Lbp antibody, LOC100472839 antibody
- 背景
- Background: Natural LBP is a 58KD glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNFα). It acts as opsonin for GRAM negative cells, LPS, neutrophiles and granulocytes.
- 分子量
- ~58kDa
- 基因ID
- 16803
- UniProt
- Q61805
- 途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process
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