CD14 抗体 (AA 147-152)
-
- 抗原 See all CD14 抗体
- CD14
-
抗原表位
- AA 147-152
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This CD14 antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Agonist (Agon)
- 特异性
- Soluble and membrane bound human CD14. The antibody does'nt significant block LPS binding to membrane bound CD14.
- 纯化方法
- Protein G affinity column
- 免疫原
- human Monocytes
- 克隆位点
- BiG2
- 亚型
- IgG1
- Top Product
- Discover our top product CD14 Primary Antibody
-
-
- 应用备注
- no significant inhibition of LPS binding to CD14
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Reconstitute with bidistilled water
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, pH 7.7
- 储存液
- Without preservative
- 储存条件
- -20 °C,-80 °C
-
-
Differential impact of substitution of amino acids 9-13 and 91-101 of human CD14 on soluble CD14-dependent activation of cells by lipopolysaccharide." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 11, pp. 6035-44, (1999) (PubMed).
: "Binding of bacterial peptidoglycan to CD14." in: The Journal of biological chemistry, Vol. 273, Issue 15, pp. 8680-90, (1998) (PubMed).
: "Low endotoxic potential of Legionella pneumophila lipopolysaccharide due to failure of interaction with the monocyte lipopolysaccharide receptor CD14." in: Infection and immunity, Vol. 66, Issue 9, pp. 4151-7, (1998) (PubMed).
: "
-
Differential impact of substitution of amino acids 9-13 and 91-101 of human CD14 on soluble CD14-dependent activation of cells by lipopolysaccharide." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 11, pp. 6035-44, (1999) (PubMed).
-
- 抗原
- CD14
- 别名
- CD14 (CD14 产品)
- 别名
- CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
- 背景
- Background: biG 2 represents an excellent marker for CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, weekly at surface of neutrophiles like Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 Molecule has been reported to be a receptor for endotoxin. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for LPS-LBP (lipopolysaccharide binding protein)-complexes.
- 分子量
- ~50kDa
- 基因ID
- 929
- NCBI登录号
- NP_000582
- UniProt
- P08571
- 途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
-