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CD40 抗体

CD40 适用: 人, 犬 FACS, IHC, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal LOB7-6 unconjugated
产品编号 ABIN337317
发货至: 中国
  • 抗原 See all CD40 抗体
    CD40
    适用
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    人, 犬
    宿主
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    小鼠
    克隆类型
    • 148
    • 90
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    单克隆
    标记
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    This CD40 antibody is un-conjugated
    应用范围
    • 142
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    品牌
    IHC-plus™
    特异性
    Recognizes the human CD40 cell surface antigen, a 48kD glycoprotein expressed by B lymphocytes and weakly by some monocytes. CD40 is involved in the process of B cell selection in germinal centers and is vital in T cell-B cell interactions.
    纯化方法
    Protein A purified
    免疫原


    Type of Immunogen: Native protein
    克隆位点
    LOB7-6
    亚型
    IgG2a
    Top Product
    Discover our top product CD40 Primary Antibody
  • 应用备注
    Approved: Flo (20 μg/mL), IHC, IHC-Fr (1 - 10 μg/mL), IHC-P (10 μg/mL), IP

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Immunohistochemistry: This product requires protein digestion pre-treatment of paraffin embedded sections prior to staining e. g. pronase or trypsin. Histology Positive Control Tissue: Human Tonsil.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Tris buffered saline, 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing. Store undiluted.
    储存条件
    4 °C,-20 °C
    储存方法
    4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.
  • 抗原
    CD40
    别名
    CD40 (CD40 产品)
    别名
    Bp50 antibody, CDW40 antibody, TNFRSF5 antibody, p50 antibody, AI326936 antibody, GP39 antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TRAP antibody, Tnfrsf5 antibody, TNFSF5 antibody, CD40 molecule antibody, CD40 antigen antibody, CD40 antibody, Cd40 antibody
    背景
    Name/Gene ID: CD40
    Family: TNF Receptor

    Synonyms: CD40, B-cell surface antigen CD40, B cell-associated molecule, B cell surface antigen CD40, CD40 antigen, CD40 type II isoform, p50, Bp50, CD40L receptor, CDW40, TNFRSF5
    基因ID
    958
    UniProt
    P25942
    途径
    NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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