OB Cadherin 抗体
(2 references)-
- 抗原 See all OB Cadherin (CDH11) 抗体
- OB Cadherin (CDH11) (Cadherin 11 (CDH11))
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适用
- 人, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This OB Cadherin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
- 特异性
- Human and rat.
- 纯化方法
- Protein A affinity column
- 免疫原
- 16A is a mouse monoclonal IgG1 antibody obtained by fusion of SP2/0 mouse myeloma cells with spleen cells from a mouse immunized with affinity purified extracellular domain of human cadherin-11-GST fusion protein.
- 克隆位点
- 16A
- 亚型
- IgG1
- Top Product
- Discover our top product CDH11 Primary Antibody
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anti-Cadherin 11 (CDH11) (AA 54-612) antibody
CDH11 适用: 人 WB, ELISA, IP, FACS, Func 宿主: 小鼠 Monoclonal 1A5 unconjugated
anti-Cadherin 11 (CDH11) (AA 468-617) antibodyCDH11 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 4E12G10 unconjugated
anti-Cadherin 11 (CDH11) (AA 54-612) antibodyCDH11 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1H1 unconjugated
anti-Cadherin 11 (CDH11) (AA 637-796) antibodyCDH11 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 11 (CDH11) (AA 310-360) antibodyCDH11 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 11 (CDH11) (AA 509-617) antibodyCDH11 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4D10 unconjugated
anti-Cadherin 11 (CDH11) (Internal Region) antibodyCDH11 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 11 (CDH11) (AA 374-595) antibodyCDH11 适用: 人 WB, ELISA, IHC (fro), ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 11 (CDH11) (AA 637-796) antibodyCDH11 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cadherin 11 (CDH11) (AA 509-617) antibodyCDH11 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
- 16A recognizes the extracellular domain of cadherin-11. 16A is suitable for immunoblotting, immunocytochemistry and immunohistochemistry on frozen sections when using a PBS buffer containing 0.1 mM CaCl 2 and 0.1 mM MgCl 2 . Optimal antibody dilution should be determined by titration, recommended range is 1:25 - 1:50 for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent, and 1:25 - 1:250 for immunoblotting applications.
- 限制
- 仅限研究用
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- 储存条件
- 4 °C
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: "Cadherin switching in human prostate cancer progression." in: Cancer research, Vol. 60, Issue 13, pp. 3650-4, (2000) (PubMed).
: "Complex cadherin expression in human prostate cancer cells." in: International journal of cancer. Journal international du cancer, Vol. 85, Issue 3, pp. 446-50, (2000) (PubMed).
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: "Cadherin switching in human prostate cancer progression." in: Cancer research, Vol. 60, Issue 13, pp. 3650-4, (2000) (PubMed).
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- 抗原
- OB Cadherin (CDH11) (Cadherin 11 (CDH11))
- 别名
- OB-Cadherin / Cadherin-11 (CDH11 产品)
- 别名
- cad11 antibody, cdhob antibody, osf-4 antibody, Xcad-11 antibody, MGC108014 antibody, OB-cadherin antibody, cadherin-11 antibody, Cad11 antibody, cdhvn antibody, vnc antibody, CAD11 antibody, CDHOB antibody, OB antibody, OSF-4 antibody, cadherin 11 antibody, cadherin 11, type 2, OB-cadherin (osteoblast) antibody, cadherin 11 S homeolog antibody, CDH11 antibody, cdh11 antibody, Cdh11 antibody, cdh11.S antibody
- 背景
- Cadherins constitute a family of transmembrane glycoproteins involved in Ca 2+ -dependent cell-cell interactions. The members of this family are differentially expressed in various tissues. They function in the maintenance of tissue integrity and morphogenesis. The cadherins generally contain five extracellular repeats, a transmembrane domain and a cytoplasmic tail that binds to the catenin family of cytoskeletal anchoring proteins which also function as signal transducers. The extracellular domains are responsible for the specificity of homophilic interactions between cells expressing the same cadherin. Cadherins are divided into type I and type II subgroups. Type I cadherins include epithelial cadherin (E-cadherin, cadherin-1 or uvomorulin), neural cadherin (N-cadherin or cadherin-2), placental cadherin (P-cadherin or cadherin-3) and retinal cadherin (R-cadherin or cadherin-4). Kidney cadherin (K-cadherin or cadherin-6) and osteoblast cadherin (OB-cadherin or cadherin-11) are type II cadherins. The progression of carcinomas is associated with the loss of epithelial morphology and a concomitant acquisition of a more mesenchymal phenotype, which is thought to contribute to the invasive and/or metastatic behavior. A putative role for cadherin-11 in these late stages of tumor progression is based on the fact that migration of mesenchymal cells is facilitated when cadherin-11 is highly expressed.
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