KRT4 抗体
(6 references)-
- 抗原 See all KRT4 抗体
- KRT4 (Keratin 4 (KRT4))
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适用
- 人, 犬, Cat, 斑马鱼
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KRT4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Human, canine and feline.
- 纯化方法
- Purified
- 免疫原
- 6B10 is a mouse monoclonal IgG1 antibody derived by fusion of SP2/0 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with a cytokeratin preparation extracted from human esophagus.
- 克隆位点
- 6B10
- 亚型
- IgG1
- Top Product
- Discover our top product KRT4 Primary Antibody
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anti-Keratin 4 (KRT4) (AA 152-457) antibody
KRT4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 4 (KRT4) (AA 194-300) antibodyKRT4 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5H5 unconjugated
anti-Keratin 4 (KRT4) antibodyKRT4 适用: 人, 大鼠, 小鼠 WB, IF (cc), IHC (p) 宿主: 兔 Monoclonal 2F9 unconjugated
anti-Keratin 4 (KRT4) (AA 181-292) antibodyKRT4 适用: 人 IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal KRT4-2804 unconjugated
anti-Keratin 4 (KRT4) (AA 1-534) antibodyKRT4 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Keratin 4 (KRT4) (AA 317-454) antibodyKRT4 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Keratin 4 (KRT4) (AA 256-360) antibodyKRT4 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc), IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Keratin 4 (KRT4) (AA 1-200) antibodyKRT4 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Keratin 4 (KRT4) (AA 386-415), (C-Term) antibodyKRT4 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18906 unconjugated
anti-Keratin 4 (KRT4) antibodyKRT4 适用: 人, 小鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- 6B10 reacts exlcusively with cytokeratin 4 which is present in non-cornifying squamous epithelium, including cornea and transitional epithelium. Cells in certain ciliated pseudo-stratified epithelia and ductal epithelia of various exocrine glands are also positive for 6B10. 6B10 is useful for immunocytochemistry, immunohistochemistry on frozen and tissues, immunoblotting and flow cytometry. Optimal antibody dilution should be determined by titration, recommended range is 1:25 - 1:200 for flow cytometry, and for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent, and 1:100 - 1:1000 for immunoblotting applications.
- 限制
- 仅限研究用
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- 储存条件
- 4 °C
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: "Four-color multiparameter DNA flow cytometric method to study phenotypic intratumor heterogeneity in cervical cancer." in: Cytometry, Vol. 39, Issue 2, pp. 96-107, (2000) (PubMed).
: "Immunohistochemistry with keratin monoclonal antibodies in canine tissues: urogenital tract, respiratory tract, (neuro-)endocrine tissues, choroid plexus and spinal cord." in: Zentralblatt für Veterinärmedizin. Reihe A, Vol. 39, Issue 10, pp. 721-40, (1993) (PubMed).
: "Cytokeratins as markers of initial stages of squamous metaplasia in feline mammary carcinomas." in: American journal of veterinary research, Vol. 54, Issue 7, pp. 1095-102, (1993) (PubMed).
: "Patterns of expression of feline cytokeratins in healthy epithelia and mammary carcinoma cells." in: American journal of veterinary research, Vol. 53, Issue 3, pp. 304-14, (1992) (PubMed).
: "Characterization of subcolumnar reserve cells and other epithelia of human uterine cervix. Demonstration of diverse cytokeratin polypeptides in reserve cells." in: Virchows Archiv. B, Cell pathology including molecular pathology, Vol. 54, Issue 2, pp. 98-110, (1988) (PubMed).
: "Cell type heterogeneity of cytokeratin expression in complex epithelia and carcinomas as demonstrated by monoclonal antibodies specific for cytokeratins nos. 4 and 13." in: Experimental cell research, Vol. 162, Issue 1, pp. 97-113, (1986) (PubMed).
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: "Four-color multiparameter DNA flow cytometric method to study phenotypic intratumor heterogeneity in cervical cancer." in: Cytometry, Vol. 39, Issue 2, pp. 96-107, (2000) (PubMed).
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- 抗原
- KRT4 (Keratin 4 (KRT4))
- 别名
- Cytokeratin 4 / Keratin K4 (KRT4 产品)
- 别名
- cb59 antibody, etID20321.6 antibody, krt8 antibody, wu:fa91a11 antibody, wu:fd19e09 antibody, wu:fl23c09 antibody, zf-K8 antibody, CK-4 antibody, CK4 antibody, CYK4 antibody, K4 antibody, Kb4 antibody, AW108092 antibody, Krt-2.4 antibody, Krt2-4 antibody, keratin 4 antibody, krt4 antibody, KRT4 antibody, Krt4 antibody
- 背景
- Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
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