KRT14 抗体
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- 抗原 See all KRT14 抗体
- KRT14 (Keratin 14 (KRT14))
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适用
- 人, 大鼠, Pig, 犬
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KRT14 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Human, rat, canine and swine.
- 纯化方法
- Purified
- 免疫原
- RCK107 is a mouse monoclonal IgG3 antibody derived by fusion of SP2/0-Ag14 mouse myeloma cells with spleen cells from a mouse immunized with a cytoskeletal preparation of TR146 epithelial cells.
- 克隆位点
- RCK107
- 亚型
- IgG1
- Top Product
- Discover our top product KRT14 Primary Antibody
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- 应用备注
- RCK107 reacts exclusively with cytokeratin 14 which is present in basal cell compartments of stratified and combined epithelia. RCK107 is suitable for immunocytochemistry, immunohistochemistry on frozen sections, flow cytometry and immunoblotting. Optimal antibody dilution should be determined by titration, recommended range is 1:100 - 1:200 for flow cytometry, and for immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent, and 1:100 - 1:1000 for immunoblotting applications.
- 限制
- 仅限研究用
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- 浓度
- 1 mg/ml
- 储存条件
- 4 °C
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T cells fail to develop in the human skin-cell explants system, an inconvenient truth." in: BMC immunology, Vol. 12, Issue 1, pp. 17, (2011) (PubMed).
: "Demonstration of intermediate cells during human prostate epithelial differentiation in situ and in vitro using triple-staining confocal scanning microscopy." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 80, Issue 8, pp. 1251-8, (2000) (PubMed).
: "Immunohistochemistry with keratin monoclonal antibodies in canine tissues: urogenital tract, respiratory tract, (neuro-)endocrine tissues, choroid plexus and spinal cord." in: Zentralblatt für Veterinärmedizin. Reihe A, Vol. 39, Issue 10, pp. 721-40, (1993) (PubMed).
: "The expression of keratins, vimentin, neurofilament proteins, smooth muscle actin, neuron-specific enolase, and synaptophysin in tumors of the specific glands in the canine anal region." in: Veterinary pathology, Vol. 30, Issue 4, pp. 352-61, (1993) (PubMed).
: "Expression of intermediate filament proteins in the adult human vestibular labyrinth." in: The Annals of otology, rhinology, and laryngology, Vol. 101, Issue 6, pp. 479-86, (1992) (PubMed).
: "Keratin expression in cervical cancer." in: The American journal of pathology, Vol. 141, Issue 2, pp. 497-511, (1992) (PubMed).
: "Basal-cell keratins in cervical reserve cells and a comparison to their expression in cervical intraepithelial neoplasia." in: The American journal of pathology, Vol. 140, Issue 3, pp. 601-12, (1992) (PubMed).
: "Laminin and type VII collagen distribution in different types of human lung carcinoma: correlation with expression of keratins 14, 16, 17 and 18." in: Histopathology, Vol. 20, Issue 4, pp. 295-303, (1992) (PubMed).
: "Basal cell-specific and hyperproliferation-related keratins in human breast cancer." in: The American journal of pathology, Vol. 138, Issue 3, pp. 751-63, (1991) (PubMed).
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T cells fail to develop in the human skin-cell explants system, an inconvenient truth." in: BMC immunology, Vol. 12, Issue 1, pp. 17, (2011) (PubMed).
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- 抗原
- KRT14 (Keratin 14 (KRT14))
- 别名
- Cytokeratin 14 / Keratin K14 (KRT14 产品)
- 别名
- CK14 antibody, EBS3 antibody, EBS4 antibody, K14 antibody, NFJ antibody, AI626930 antibody, Krt-1.14 antibody, Krt1-14 antibody, Ka14 antibody, ouro2 antibody, keratin 14 antibody, keratin 14, type I L homeolog antibody, KRT14 antibody, Krt14 antibody, krt14.L antibody
- 背景
- Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
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