KDM5A 抗体 (AA 1416-1434)
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- 抗原 See all KDM5A 抗体
- KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))
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抗原表位
- AA 1416-1434
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This KDM5A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- 特异性
- Specific to human and mouse RBP2. Can detect endogenous levels of RBP2.
- 纯化方法
- Purified
- 过滤
- Sterile filtered
- 免疫原
- A synthetic peptide corresponding to human RBP2, aa 1416-1434.
- 克隆位点
- 18E8
- 亚型
- IgG2a kappa
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- 应用备注
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1. Western blotting: ~1 g/mL
2. Immunofluorescence staining
3. Flow Cytometry: 1 g for 10^6 cells - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, 50 % glycerol
- 储存液
- Azide free
- 储存条件
- -20 °C
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Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation." in: Molecular cell, Vol. 31, Issue 4, pp. 520-30, (2008) (PubMed).
: "RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3." in: Cell, Vol. 128, Issue 6, pp. 1063-76, (2007) (PubMed).
: "The retinoblastoma binding protein RBP2 is an H3K4 demethylase." in: Cell, Vol. 128, Issue 5, pp. 889-900, (2007) (PubMed).
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Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation." in: Molecular cell, Vol. 31, Issue 4, pp. 520-30, (2008) (PubMed).
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- 抗原
- KDM5A (Lysine (K)-Specific Demethylase 5A (KDM5A))
- 别名
- KDM5A (KDM5A 产品)
- 别名
- Jarid1a antibody, JARID1A antibody, RBBP-2 antibody, RBBP2 antibody, RBP2 antibody, AA409370 antibody, C76986 antibody, Rbbp2 antibody, lysine demethylase 5A antibody, lysine (K)-specific demethylase 5A antibody, Kdm5a antibody, KDM5A antibody
- 背景
- RBP2 was originally identified as a retinoblastoma binding protein. It is also known as JARID1A (Jumonji, AT rich interactive domain 1A). RBP2 plays both negative and positive roles in RB- mediated transcriptional activation, depending on the kinds of genes and regulates differentiation by its function as an H3K4 histone demethylase.
- UniProt
- P29375
- 途径
- Chromatin Binding, Warburg Effect
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