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CD14 抗体 (N-Term)

Name: CD14 抗体 (N-Term)
SKU: ABIN319685
Availability: OutOfStock

CD14 适用: 人, 猴 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal UCHM1 unconjugated

产品编号 ABIN319685

发货至: 中国

Datasheet as PDF

抗原 See all CD14 抗体

CD14
抗原表位
9

6

5

4

4

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-4, N-Term
适用
230

38

37

25

24

23

23

23

18

16

15

15

14

14

13

10

8

7

6

5

5

2

1

1
人, 猴
宿主
204

52

16

3

1
小鼠
Compatible Secondaries
克隆类型
222

54
单克隆
标记
115

33

23

19

13

5

5

4

4

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD14 antibody is un-conjugated
应用范围
208

82

62

50

48

45

21

14

13

11

7

4

4

3

3

3

2

2

2

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

纯化方法

Affinity chromatography on Protein G

免疫原

Human Thymocytes followed by peripheral blood mononuclear cells. Spleen cells from mice immunised with human thymocytes and PBLs were fused with cells from the NS1-Ag4/1 mouse myeloma cell line.

克隆位点

UCHM1

亚型

IgG2a

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应用备注

Flow cytometry. Immunhistology on frozen sections. Recommended Positive Control: Tonsil. Immunprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

1.0 mg/mL

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

CD14

别名

CD14 (CD14 产品)

别名

CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody

背景

CD14 is a single copy gene encoding 2 protein forms: a 50 to 55 kDa glycosylphosphatidylinositol anchored membrane protein (mCD14) and a monocyte or liver derived soluble serum protein (sCD14) that lacks the anchor. Both molecules are critical for lipopolysaccharide (LPS) dependent signal transduction, and sCD14 confers LPS sensitivity to cells lacking mCD14. Increased sCD14 levels are associated with inflammatory infectious diseases and high mortality in gram negative shock. CD14 also appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein

基因ID

9606

UniProt

P08571

途径

TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades