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ATR 抗体 (Ser428)

ATR 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN319379
发货至: 中国
  • 抗原 See all ATR 抗体
    ATR (Ataxia Telangiectasia and Rad3 Related (ATR))
    抗原表位
    • 2
    • 1
    • 1
    • 1
    • 1
    Ser428
    适用
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 5
    • 2
    克隆类型
    • 5
    • 2
    多克隆
    标记
    • 7
    This ATR antibody is un-conjugated
    应用范围
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of total ATR protein.
    纯化方法
    Immunoaffinity Chromatography.
    免疫原
    The antiserum was produced against synthesized non-phosphopeptide derived from human ATR around the phosphorylation site of Serine 428 (G-I-SP-P-K).
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    Discover our top product ATR Primary Antibody
  • 应用备注
    Immunohistochemistry (1/50-1/100).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at-20 °C.
  • 抗原
    ATR (Ataxia Telangiectasia and Rad3 Related (ATR))
    别名
    ATR / FRP1 (ATR 产品)
    别名
    ATR antibody, si:dkey-231j24.1 antibody, FCTCS antibody, FRP1 antibody, MEC1 antibody, SCKL antibody, SCKL1 antibody, XATR antibody, frp1 antibody, mec1 antibody, sckl antibody, sckl1 antibody, ARABIDOPSIS THALIANA ATAXIA TELANGIECTASIA-MUTATED AND RAD3-RELATED antibody, ATATR antibody, ATRAD3 antibody, Ataxia telangiectasia-mutated and RAD3-related antibody, MHK7.5 antibody, MHK7_5 antibody, ataxia telangiectasia and Rad3 related antibody, ATR serine/threonine kinase antibody, ATR serine/threonine kinase L homeolog antibody, Ataxia telangiectasia-mutated and RAD3-like protein antibody, Atr antibody, ATR antibody, atr antibody, atr.L antibody
    背景
    Ataxia Telangiectasia Mutated (ATM) and Rad 3-related protein (ATR) is a phosphatidylinositol kinase (PK)-related kinase which functions in response to DNA damage and repair as well as at DNA replication checkpoints during the cell cycle. ATR is a member of the DNA-PK kinases closely related to ATM and DNA-PK for which DNA stimulates the observed kinase activity. Chromosomal remodeling proteins have also been reported to associate with ATR complexes. Several known components of the NuRD complex including histone deacetylase 1 (HDAC1), HDAC2, and CHD4.Synonyms: Ataxia telangiectasia and Rad3-related protein, FRAP-related protein 1, Serine/threonine-protein kinase ATR
    基因ID
    545
    NCBI登录号
    NP_001175
    UniProt
    Q13535
    途径
    p53 Pathway, Apoptosis, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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